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银屑病的共病情况——女性发病率更高:一项前瞻性研究。

Comorbid conditions in psoriasis - Higher frequency in females: A prospective study.

作者信息

Kumar Parimalam, Thomas Jayakar

机构信息

Department of Dermatology, Stanley Medical College, Chennai, India.

出版信息

Indian Dermatol Online J. 2012 May;3(2):105-8. doi: 10.4103/2229-5178.96701.

DOI:10.4103/2229-5178.96701
PMID:23130282
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3481875/
Abstract

AIM

To study the association of obesity, diabetes, hypertension, and abnormal lipid profile in women above 40 years of age with psoriasis.

MATERIALS AND METHODS

Two hundred consecutive female patients with psoriasis attending private clinics were included. Complete general, systemic, and dermatological examinations were performed. Blood pressure, blood sugar, and lipid profile were recorded in all patients and the findings analyzed.

RESULTS

Of 200 patients, 45 were obese. Eighty-eight patients had diabetes mellitus and 29 had dyslipidemia of whom 13 and 18, respectively, were detected at the time of enrolment. All 25 patients with systemic hypertension were on treatment. A total of 177 (88.5%) patients had one or more comorbid conditions. This frequency is much higher when compared to other Indian studies where the sample included patients of both sexes.

摘要

目的

研究40岁以上女性肥胖、糖尿病、高血压及血脂异常与银屑病之间的关联。

材料与方法

纳入200例连续就诊于私立诊所的女性银屑病患者。进行全面的全身及皮肤科检查。记录所有患者的血压、血糖及血脂情况,并对结果进行分析。

结果

200例患者中,45例肥胖。88例患有糖尿病,29例血脂异常,其中分别有13例和18例在入组时被检测出。所有25例系统性高血压患者均在接受治疗。共有177例(88.5%)患者有一种或多种合并症。与其他纳入了男女患者样本的印度研究相比,该频率要高得多。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2531/3481875/2f4e09c36e6f/IDOJ-3-105-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2531/3481875/06fc0a4b2f46/IDOJ-3-105-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2531/3481875/d3f9a6d5709d/IDOJ-3-105-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2531/3481875/0ec2cb88b2ab/IDOJ-3-105-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2531/3481875/2f4e09c36e6f/IDOJ-3-105-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2531/3481875/06fc0a4b2f46/IDOJ-3-105-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2531/3481875/d3f9a6d5709d/IDOJ-3-105-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2531/3481875/0ec2cb88b2ab/IDOJ-3-105-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2531/3481875/2f4e09c36e6f/IDOJ-3-105-g004.jpg

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本文引用的文献

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Co-morbidity and age-related prevalence of psoriasis: Analysis of health insurance data in Germany.共病和与年龄相关的银屑病患病率:德国健康保险数据的分析。
Acta Derm Venereol. 2010 Mar;90(2):147-51. doi: 10.2340/00015555-0770.
2
Managing comorbid disease in patients with psoriasis.银屑病患者合并疾病的管理。
BMJ. 2010 Jan 15;340:b5666. doi: 10.1136/bmj.b5666.
3
Psoriasis and the risk of diabetes and hypertension: a prospective study of US female nurses.银屑病与糖尿病和高血压风险:一项对美国女护士的前瞻性研究
Arch Dermatol. 2009 Apr;145(4):379-82. doi: 10.1001/archdermatol.2009.48.
4
Psoriatic arthritis: genetic susceptibility and pharmacogenetics.银屑病关节炎:遗传易感性与药物遗传学
Pharmacogenomics. 2008 Feb;9(2):195-205. doi: 10.2217/14622416.9.2.195.
5
Psoriasis--recent advances in understanding its pathogenesis and treatment.银屑病——对其发病机制和治疗理解的最新进展
J Am Acad Dermatol. 2005 Jul;53(1 Suppl 1):S94-100. doi: 10.1016/j.jaad.2005.04.035.
6
Increased risk for cardiovascular mortality in psoriasis inpatients but not in outpatients.银屑病住院患者心血管死亡风险增加,但门诊患者未增加。
Eur J Epidemiol. 2004;19(3):225-30. doi: 10.1023/b:ejep.0000020447.59150.f9.
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Lifetime risk for diabetes mellitus in the United States.美国糖尿病的终生风险。
JAMA. 2003 Oct 8;290(14):1884-90. doi: 10.1001/jama.290.14.1884.
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Prevalence, expenditures, and complications of multiple chronic conditions in the elderly.老年人多种慢性病的患病率、医疗支出及并发症
Arch Intern Med. 2002 Nov 11;162(20):2269-76. doi: 10.1001/archinte.162.20.2269.
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Diseases associated with psoriasis in a general population of 159,200 middle-aged, urban, native Swedes.
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