Ostini Remo, Roughead Elizabeth E, Kirkpatrick Carl M J, Monteith Greg R, Tett Susan E
School of Pharmacy, The University of Queensland, Brisbane, Queensland, Australia.
Int J Pharm Pract. 2012 Dec;20(6):349-57. doi: 10.1111/j.2042-7174.2012.00210.x. Epub 2012 May 18.
To review current literature with the objective of developing strategies and recommendations to enhance patient safety and minimise clinical issues with look-alike, sound-alike medication names.
A comprehensive search of the PubMed database and an Australian online repository of Quality Use of Medicines projects was conducted to identify publications addressing look-alike, sound-alike medication problems. Author networks, grey literature and the reference lists of published articles were also used to identify additional material.
Thirty-two publications describing the extent of the specific problem and recommending solutions were identified. The majority of these publications provided a qualitative assessment of the issues, with few quantitative estimates of the severity of the problem and very little intervention research. As a result, most recommendations for addressing the problem are the result of expert deliberations and not experimental research. This will affect the capacity of the recommendations to ameliorate and resolve problems caused by look-alike, sound-alike medication names. Themes identified from articles included the nature and causes of look-alike, sound-alike problems, potential solutions and recommendations.
There are many existing medications which can potentially cause clinical issues due to mix-ups because of similar sounding or looking medication names. This confusion can be lethal for some medication errors. A multifaceted, integrated approach involving all aspects of the medication use process, from initial naming of INN through to consumer education, is suggested to minimise this issue for medication safety.
回顾当前文献,旨在制定策略和建议,以提高患者安全,并最大限度减少因药品名称相似而导致的临床问题。
全面检索PubMed数据库以及澳大利亚药品合理使用项目在线存储库,以识别涉及药品名称相似问题的出版物。还利用作者网络、灰色文献和已发表文章的参考文献列表来识别其他资料。
共识别出32篇描述该特定问题的严重程度并推荐解决方案的出版物。这些出版物大多对问题进行了定性评估,很少有对问题严重程度的定量估计,干预研究也非常少。因此,大多数解决该问题的建议是专家审议的结果,而非实验研究的结果。这将影响这些建议改善和解决因药品名称相似而导致问题的能力。从文章中识别出的主题包括药品名称相似问题的性质和原因、潜在解决方案及建议。
由于药品名称发音或外观相似,现有许多药物可能因混淆而引发临床问题。这种混淆对某些用药错误可能是致命的。建议采用一种多方面、综合的方法,涵盖药品使用过程的各个方面,从国际非专利药品名称的最初命名到消费者教育,以将该问题对用药安全的影响降至最低。