I,M,Sechenov First Moscow State Medical University, Moscow, Russia.
EPMA J. 2012 Nov 9;3(1):16. doi: 10.1186/1878-5085-3-16.
In the present state of healthcare, usual medical care is generally given to the already diseased person, while the key link-personal health monitoring underlain by predictive, preventive, and personalised medicine (PPPM) techniques that are being intensively elaborated worldwide-is simply missing. It is this link, based on the recognition of subclinical conditions, prediction, and further preventive measures, that is capable of regulating morbidity and diminishing the rates of disability among able-bodied population, thus significantly cutting the traditionally high costs of treating the already diseased people. To achieve the above-mentioned goal-the elaboration of the PPPM concept and its practical implementation-it is necessary to create a fundamentally new strategy based upon the subclinical recognition of the signs-bioindicators of cryptic abnormalities long before the disease clinically manifests itself. The implementation of PPPM programme requires an adjusted technology for the proper interpretation of diagnostic data, which would allow for the current 'physician-patient' model to be gradually replaced by a novel model, 'medical advisor-healthy men-at-risk'. This is the reason for an additional need in organising combinatorial scientific, clinical, training and educational projects in the area of PPPM to elicit the content of this new branch of medicine.
在当前的医疗保健状态下,通常的医疗护理是给予已经患病的人,而关键的环节——个人健康监测,是基于预测、预防和个性化医学(PPPM)技术的,但这一环节在全世界范围内都被忽视了。正是基于对亚临床状况的认识、预测和进一步的预防措施,这种联系能够调节发病率,减少健全人群的残疾率,从而显著降低治疗已患病人群的传统高成本。为了实现上述目标,即阐述 PPPM 概念并将其付诸实践,有必要在亚临床识别疾病出现前很久就已经隐匿异常的生物标志物的迹象的基础上,制定一项全新的战略。实施 PPPM 计划需要一种调整后的技术来正确解释诊断数据,这将允许当前的“医患”模式逐渐被一种新的模式“医疗顾问——健康高危人群”所取代。这就是为什么需要在 PPPM 领域组织组合式科学、临床、培训和教育项目,以引出这一新医学分支的内容。