Department of Otorhinolaringology, Head and Neck Surgery, Hospital Angeles Lomas, Mexico City, Mexico.
Eur Arch Otorhinolaryngol. 2013 Mar;270(3):995-9. doi: 10.1007/s00405-012-2244-8. Epub 2012 Nov 13.
The objectives of this study were: (1) to determine the percentage of patients seen in a private laryngology clinic with voice-related disorders previously diagnosed with and treated for laryngopharyngeal reflux (LPR); (2) to determine how many of those patients are found to have disorders other than LPR as a cause for their voice disorder. A retrospective, chart-review analysis of new patients was conducted from January 2005 through December 2007 in a private laryngology clinic setting. Patients with a previous diagnosis of LPR as the cause of hoarseness, with or without anti-reflux treatment were included. Incomplete charts and patients with additional diagnoses besides LPR where excluded. Patient charts were analyzed in search of different variables including chief complaint, previous medications and final diagnosis among others. 784 consecutive charts were reviewed. Inclusion criteria were met in 105 charts. 82 % had no improvement or felt worse after previous anti-reflux treatment while 18 % had significant or mild improvement. However, all patients remained with some degree of hoarseness. Final diagnosis by the author was diverse though none of the patients had laryngopharyngeal reflux as a final diagnosis and none of them noted worsening of their voice after respective treatment. Only 6 % felt the same after treatment and 9 % could not be found for follow-up. LPR has become an over-diagnosed entity. With a thorough history, vocal capability testing and physical exam, an accurate diagnosis for hoarseness can be made in the vast majority of cases. LPR may not be the cause of voice disorders and should not be assigned as a de facto diagnosis just because the cause of hoarseness is not readily identifiable.
(1)确定在私人喉科诊所就诊的患有与喉咽反流(LPR)相关的声音障碍的患者中,之前被诊断和治疗过 LPR 的患者的比例;(2)确定这些患者中有多少人被发现患有除 LPR 以外的其他疾病作为其声音障碍的原因。对 2005 年 1 月至 2007 年 12 月在私人喉科诊所就诊的新患者进行了回顾性图表审查分析。包括之前被诊断为 LPR 是声音嘶哑原因的患者,无论是否进行了抗反流治疗。不包括图表不完整和除 LPR 以外还有其他诊断的患者。分析患者图表以寻找不同的变量,包括主要抱怨、以前的药物治疗和最终诊断等。共审查了 784 份连续图表。105 份图表符合纳入标准。82%的患者在先前的抗反流治疗后没有改善或感觉更糟,而 18%的患者有显著或轻度改善。然而,所有患者仍有一定程度的声音嘶哑。尽管作者的最终诊断多种多样,但没有患者被诊断为喉咽反流,也没有患者在各自的治疗后声音恶化。只有 6%的患者在治疗后感觉相同,9%的患者无法进行随访。LPR 已经成为一种被过度诊断的疾病。通过详细的病史、嗓音能力测试和体格检查,可以在绝大多数情况下对声音嘶哑做出准确的诊断。LPR 可能不是声音障碍的原因,不应该仅仅因为声音嘶哑的原因不容易确定就将其作为事实上的诊断。