缓解期炎症性肠病患者的疲劳和与疾病相关的担忧；这是否反映了并存的类似 IBS 的症状？一份简短报告。
Fatigue and disease-related worries among inflammatory bowel disease patients in remission; is it a reflection of coexisting IBS-like symptoms? A short report.
机构信息
Østfold University College, Fredrikstad, Norway.
出版信息
J Psychosom Res. 2012 Dec;73(6):469-72. doi: 10.1016/j.jpsychores.2012.08.009. Epub 2012 Aug 31.
OBJECTIVES
Irritable bowel syndrome (IBS) like symptoms and fatigue are frequently reported in quiescent inflammatory bowel disease (IBD). We hypothesized that coexisting IBS-like symptoms might be associated with increased levels of fatigue and disease-related worries.
METHODS
A total of 140 IBD outpatients were assessed. Cut-off for remission was <4 and <3 on the disease activity indices SCDAI and SCCAI. In addition patients on current steroid treatment were excluded. A diagnosis of IBS was based on the Rome criteria. Fatigue was measured with the Fatigue Questionnaire (FQ), disease related worries with the Rating Form of IBD Patient Concerns (RFIPC).
RESULTS
Eighty-nine patients fulfilled the criteria for remission. Of these 89 patients, 21 and 30 were IBS positive according to the Rome II and III criteria, respectively. FQ scores were significantly elevated in IBS positive UC patients. Clinical significant differences were also found in relation to RFIPC scores.
CONCLUSION
Coexisting IBS-like symptoms among IBD patients in remission are associated with an increased level of fatigue and disease-related worries.
目的
在炎症性肠病（IBD）静止期，常报告有肠易激综合征（IBS）样症状和疲劳。我们假设，共存的 IBS 样症状可能与疲劳和疾病相关担忧的水平增加有关。
方法
共评估了 140 名 IBD 门诊患者。缓解的截止值分别为 SCDAI 和 SCCAI 疾病活动指数<4 和<3。此外，排除了正在接受类固醇治疗的患者。IBS 的诊断基于罗马标准。疲劳用疲劳问卷（FQ）测量，疾病相关担忧用 IBD 患者担忧评分表（RFIPC）测量。
结果
89 名患者符合缓解标准。在这 89 名患者中，根据罗马 II 期和 III 期标准，分别有 21 名和 30 名患者为 IBS 阳性。UC 患者中 IBS 阳性的 FQ 评分显著升高。在 RFIPC 评分方面也存在显著的临床差异。
结论
缓解期 IBD 患者共存的 IBS 样症状与疲劳和疾病相关担忧水平增加有关。
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