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真菌及其真菌学对全球生物经济发展的重要性。

The importance of fungi and of mycology for a global development of the bioeconomy.

机构信息

Institute of Biotechnology and Chemistry, Faculty of Science and Technology, Aalborg University, Denmark.

出版信息

IMA Fungus. 2012 Jun;3(1):87-92. doi: 10.5598/imafungus.2012.03.01.09. Epub 2012 Jun 22.

Abstract

The vision of the European common research programme for 2014-2020, called Horizon 2020, is to create a smarter, more sustainable and more inclusive society. However, this is a global endeavor, which is important for mycologists all over the world because it includes a special role for fungi and fungal products. After ten years of research on industrial scale conversion of biowaste, the conclusion is that the most efficient and gentle way of converting recalcitrant lignocellulosic materials into high value products for industrial purposes, is through the use of fungal enzymes. Moreover, fungi and fungal products are also instrumental in producing fermented foods, to give storage stability and improved health. Climate change will lead to increasingly severe stress on agricultural production and productivity, and here the solution may very well be that fungi will be brought into use as a new generation of agricultural inoculants to provide more robust, more nutrient efficient, and more drought tolerant crop plants. However, much more knowledge is required in order to be able to fully exploit the potentials of fungi, to deliver what is needed and to address the major global challenges through new biological processes, products, and solutions. This knowledge can be obtained by studying the fungal proteome and metabolome; the biology of fungal RNA and epigenetics; protein expression, homologous as well as heterologous; fungal host/substrate relations; physiology, especially of extremophiles; and, not the least, the extent of global fungal biodiversity. We also need much more knowledge and understanding of how fungi degrade biomass in nature.The projects in our group in Aalborg University are examples of the basic and applied research going on to increase the understanding of the biology of the fungal secretome and to discover new enzymes and new molecular/bioinformatics tools.However, we need to put Mycology higher up on global agendas, e.g. by positioning Mycology as a candidate for an OECD Excellency Program. This could pave the way for increased funding of international collaboration, increased global visibility, and higher priority among decision makers all over the world.

摘要

2014-2020 年欧洲共同研究计划——“地平线 2020”的愿景是创造一个更智能、更可持续和更具包容性的社会。然而,这是一项全球性的努力,对全世界的真菌学家都很重要,因为它为真菌和真菌产品赋予了特殊的角色。经过十年的研究,工业规模的生物废物转化已经得出结论,最有效和温和的方法是利用真菌酶将顽固的木质纤维素材料转化为具有工业价值的高价值产品。此外,真菌和真菌产品在生产发酵食品方面也发挥了重要作用,可以提供储存稳定性并改善健康状况。气候变化将导致农业生产和生产力面临日益严重的压力,而在这里,解决方案很可能是将真菌用作新一代农业接种剂,以提供更健壮、更具营养效率和更能耐受干旱的作物。然而,为了充分利用真菌的潜力,为了通过新的生物过程、产品和解决方案来满足需求并应对主要的全球挑战,还需要更多的知识。这些知识可以通过研究真菌的蛋白质组和代谢组、真菌 RNA 和表观遗传学的生物学、同源和异源的蛋白质表达、真菌宿主/底物关系、生理学(特别是极端微生物学)以及全球真菌生物多样性的程度来获得。我们还需要更多的知识和理解,了解真菌如何在自然界中降解生物质。我们在奥尔堡大学的研究小组的项目是进行基础和应用研究的例子,旨在增加对真菌分泌生物学的理解,并发现新的酶和新的分子/生物信息学工具。然而,我们需要将真菌学置于全球议程的更高位置,例如将真菌学定位为经合组织卓越计划的候选学科。这可以为增加国际合作的资金、提高全球知名度以及在全球范围内提高决策者的优先级铺平道路。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/398c/3399105/02255719dfbd/ima-3-87-g001.jpg

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