Private Practice, Sassuolo, Italy.
Clin Oral Implants Res. 2014 Feb;25(2):e120-6. doi: 10.1111/clr.12073. Epub 2012 Nov 21.
The aim of this study was to clinically and histologically analyze the healing of grafted sockets by mineralized human bone allograft (MHBA) and nongrafted sockets, correlating the results with buccal plate thickness.
Thirty-one sockets were randomly split into control (CG) and treatment (MHBA grafted) (TG) groups and, subsequently, into four subgroups according to buccal plate thickness: a ≤ 1 mm and b > 1 mm. Ridge thickness, depth, and height were monitored. Four months after, at implant placement, a bone core biopsy for histologic and morphometric analyses was taken.
The differences of buccal height (TG-a -0.27 and CG-a -1.17 mm) and width (TG-a 0.55 and CG-a 2.67 mm, TG-b 0.12 and CG-b 1.17 mm) were statistically significant. The increase in bone amount CG-b (28.17%) compared with CG-a (16.98%) was statistically significant. Soft tissue amount of TG-b (54.21%) and TG-a (56.91%) was lower than that of CG-b (71.83%) and CG-a (83.01%), both being statistically significant (P = 0.002).
The results proved that thin buccal plates had a worse outcome on socket healing and that network formation by MBHA not only predisposes a successful implant insertion but also acts as size keeper.
本研究旨在通过分析矿化同种异体人骨移植物（MHBA）和未移植牙槽窝的临床和组织学愈合情况，并与颊板厚度相关联，来评估其临床效果。
31 个牙槽窝被随机分为对照组（CG）和治疗组（MHBA 移植）（TG），并根据颊板厚度进一步分为四个亚组：a≤1mm 和 b＞1mm。监测牙槽嵴厚度、深度和高度。4 个月后，在种植体植入时，进行骨芯活检以进行组织学和形态计量学分析。
在颊侧高度（TG-a-0.27 和 CG-a-1.17mm）和宽度（TG-a0.55 和 CG-a2.67mm，TG-b0.12 和 CG-b1.17mm）方面，差异具有统计学意义。与 CG-a（16.98%）相比，CG-b（28.17%）的骨量增加具有统计学意义。与 CG-b（71.83%）和 CG-a（83.01%）相比，TG-b（54.21%）和 TG-a（56.91%）的软组织量较低，差异具有统计学意义（P=0.002）。
结果表明，薄颊板对牙槽窝愈合的结果更差，而 MHBA 的网状形成不仅有利于成功植入种植体，而且还起到尺寸保持的作用。
