腺病毒41型在半容许细胞中的生长呈现多击动力学。
Adenovirus 41 growth in semi-permissive cells shows multiple-hit kinetics.
作者信息
Tiemessen C T, Kidd A H
机构信息
Department of Virology, University of the Witwatersrand, Johannesburg, South Africa.
出版信息
Arch Virol. 1990;110(3-4):239-45. doi: 10.1007/BF01311291.
PMID:2317153
Abstract
Adenovirus type 41 infection of semi-permissive Chang conjunctival cells, monitored by fluorescent focus assay, followed multiple-hit kinetics. In non-permissive human cells, type 41 showed infectivity with two-hit kinetics in the presence of type 2. Type 41 infectivity was seen to be directly proportional to input concentration (one-hit) only in 293 cells, a continuous human line expressing Ad 5 E1 products.
摘要
通过荧光灶测定法监测，41型腺病毒对半允许性的张氏结膜细胞的感染呈现多次打击动力学。在非允许性人类细胞中，41型在2型存在的情况下呈现双打击动力学的感染性。仅在表达Ad 5 E1产物的连续人类细胞系293细胞中，41型感染性才与输入浓度呈直接比例关系（单打击）。
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