Antona Denise, Baudon Claire, Freymuth François, Lamy Mathieu, Maine Catherine, Parent du Chatelet Isabelle, Lévy-Bruhl Daniel
Institut de veille sanitaire, St Maurice Cedex, France.
Med Sci (Paris). 2012 Nov;28(11):1003-7. doi: 10.1051/medsci/20122811023. Epub 2012 Nov 12.
From January 2008 to May 2012, over 22,000 cases of measles were reported in France. The highest incidence rate was observed in children below one year of age. Over 50% of cases were reported in young adults. Almost 5,000 patients were hospitalised including 1,023 with severe pneumonia, 27 with encephalitis and/or myelitis : 10 died. This situation is linked to insufficient and heterogeneous vaccination coverage with pockets of susceptible people allowing virus circulation. Although the vaccine coverage in children has now improved for both doses, the issue of convincing young susceptible adults to catch up for measles vaccination remains critical, if the elimination target is to be met, and in order to protect the most vulnerable population unable to benefit from this vaccination (children below 1 year, immunodeficient people, pregnant women).
2008年1月至2012年5月期间，法国报告了22000多例麻疹病例。一岁以下儿童的发病率最高。超过50%的病例报告发生在年轻人中。近5000名患者住院治疗，其中1023人患有严重肺炎，27人患有脑炎和/或脊髓炎，10人死亡。这种情况与疫苗接种覆盖率不足且不均衡有关，存在易感人群聚集区，使得病毒得以传播。尽管儿童两剂疫苗的接种覆盖率目前已有提高，但要实现消除目标并保护无法接种该疫苗的最脆弱人群（一岁以下儿童、免疫缺陷者、孕妇），说服易感的年轻成年人补种麻疹疫苗这一问题仍然至关重要。
