Castelli W P
Am Heart J. 1986 Aug;112(2):432-7. doi: 10.1016/0002-8703(86)90296-6.
Triglycerides make up the overwhelming proportion of dietary fat consumed in the United States and other industrialized nations. Triglyceride elevation is directly associated with relative weight and age in both sexes, oral contraceptive use in women, and the development of diabetes mellitus. Triglyceride elevations are a highly significant independent risk factor for coronary heart disease (CHD) in women. They appear to be important in men with low high-density lipoprotein (HDL) cholesterol (less than 40 ml/dl). Dangerously high levels of triglyceride are associated with a high total cholesterol/HDL cholesterol ratio, which is an excellent indicator of CHD risk in both sexes. Individuals with elevated triglycerides should be considered at risk for CHD unless the total cholesterol/HDL cholesterol ratio is under 3.5. In practice, however, only about 10% of individuals with elevated triglycerides prove to have such low total cholesterol/HDL cholesterol ratios.
在美国和其他工业化国家，饮食中摄入的脂肪绝大部分是甘油三酯。甘油三酯升高与男女的相对体重和年龄直接相关，与女性口服避孕药的使用有关，还与糖尿病的发展有关。甘油三酯升高是女性冠心病（CHD）的一个高度显著的独立危险因素。它们在高密度脂蛋白（HDL）胆固醇水平低（低于40毫升/分升）的男性中似乎也很重要。甘油三酯水平过高与总胆固醇/HDL胆固醇比值高有关，这是男女患冠心病风险的一个极佳指标。甘油三酯升高的个体应被视为有患冠心病的风险，除非总胆固醇/HDL胆固醇比值低于3.5。然而，在实际情况中，甘油三酯升高的个体中只有约10%的人总胆固醇/HDL胆固醇比值如此之低。
