Monash IVF, Healthbridge Hawthorn Private Hospital, 50 Burwood Rd., Hawthorn, VIC, Australia.
Hum Reprod. 2013 Feb;28(2):375-84. doi: 10.1093/humrep/des403. Epub 2012 Nov 23.
How do families with children conceived using donor sperm operate as the children grow up?
Families with children aged 5-13 years conceived through anonymous donor sperm function well, when compared with other family types with children of the same developmental stage.
Previous studies on family relationships after donor sperm conception have been reassuring. However, these studies have suffered from methodological limitations due to small sample sizes, respondent biases and absence of appropriate controls.
STUDY DESIGN, SIZE, DURATION: This study was an observational study comparing 79 'donor insemination' (DI) families with 987 'couple' families, 364 'single mother' and 112 'step-father' families as part of the Australian Institute of Family Studies Children and Family Life (CFL) study. CFL involved the collection of data on family functioning and child wellbeing from all resident parents through a Family and Child Questionnaire for the 'primary' parent (FACQ-P1) and a Family Relationship Questionnaire (FRQ-P2) for the 'other' parent.
PARTICIPANTS/MATERIALS, SETTING, METHODS: All questionnaires were coded with the identity known only to the researchers. The outcomes studied included parent psychological adjustment, family functioning, couple relationship, parenting and parent-child relationship. Family types were compared, separately for mothers' and fathers' reports. The results presented are the estimated means for each family type based on the final model for each outcome: post hoc comparisons between family types are reported with 95% confidence limits.
With all of the outcomes considered, there was not one result where the DI families showed poorer functioning on average than the comparison groups.
LIMITATIONS, REASON FOR CAUTION: The final sample size of DI families is 79 with an excellent response rate of nearly 80%. However, there remains some scope for response bias.
This study further reassures us that families conceived with anonymous donor sperm do not function any differently from other family types.
使用供精受孕的家庭，随着孩子的成长，其运作方式如何？
与具有相同发育阶段孩子的其他类型家庭相比，通过匿名供精受孕的家庭中，年龄在 5-13 岁的孩子成长良好。
先前关于供精受孕后家庭关系的研究结果令人安心。然而，由于样本量小、受访者偏见以及缺乏适当的对照，这些研究受到了方法学上的限制。
研究设计、规模、持续时间：这是一项观察性研究，比较了 79 个“供精人工授精”（DI）家庭、987 个“夫妻”家庭、364 个“单身母亲”家庭和 112 个“继父”家庭，这些家庭均为澳大利亚家庭研究所儿童与家庭生活（CFL）研究的一部分。CFL 通过向所有居住的父母发放家庭功能和儿童福利问卷（FACQ-P1）和家庭关系问卷（FRQ-P2），收集主要父母（FACQ-P1）和其他父母（FRQ-P2）的家庭功能和儿童福利数据。
参与者/材料、设置、方法：所有问卷都用只有研究人员知道的身份进行编码。研究的结果包括父母的心理调整、家庭功能、夫妻关系、育儿和亲子关系。分别对母亲和父亲的报告进行了家庭类型比较。呈现的结果是基于每个结果的最终模型计算的每个家庭类型的估计平均值：报告了事后家庭类型之间的比较，并附有 95%置信区间。
在考虑到所有结果的情况下，没有一个结果表明 DI 家庭的平均功能比对照组差。
局限性、谨慎的原因：DI 家庭的最终样本量为 79，响应率接近 80%，非常出色。但是，仍然存在一些响应偏差的空间。
本研究进一步让我们放心，通过匿名供精受孕的家庭与其他家庭类型的功能没有不同。
