Pillet M C, Wu T F, Adamson G D, Subak L L, Lamb E J
Department of Gynecology and Obstetrics, Stanford University School of Medicine, California.
Fertil Steril. 1990 Apr;53(4):614-9. doi: 10.1016/s0015-0282(16)53452-9.
The use of basal body temperature (BBT) recording and a single progesterone (P) level at the time of the endometrial biopsy in the late luteal phase improved our ability to predict the onset of the next menstrual period (NMP) and determine the postovulatory day (POD) in 124 regularly menstruating infertile women. We determined BBT shift using a microcomputer program, analyzed P levels by radioimmunoassay, and evaluated endometrial biopsies both prospectively (blinded) and retrospectively (with knowledge of the other variables). Serum P levels were within the normal range for the luteal phase and prospective and retrospective histological diagnoses closely agreed (82% within 2 days). The best correlation with the NMP was the BBT shift (r = 0.493) followed by P (r = 0.426) and prospective histologic dating (r = 0.390). Multiple regression analysis confirmed that use of all of the variables markedly improved the ability to estimate the POD (R2 = 0.51).
在124名月经周期规律的不孕女性中，采用基础体温（BBT）记录以及黄体晚期子宫内膜活检时的单一孕酮（P）水平，提高了我们预测下次月经期（NMP）开始时间和确定排卵后天数（POD）的能力。我们使用微机程序确定BBT变化，通过放射免疫分析法分析P水平，并对子宫内膜活检进行前瞻性（盲法）和回顾性（已知其他变量）评估。血清P水平在黄体期正常范围内，前瞻性和回顾性组织学诊断结果高度一致（82%在2天内）。与NMP相关性最好的是BBT变化（r = 0.493），其次是P（r = 0.426）和前瞻性组织学分期（r = 0.390）。多元回归分析证实，使用所有变量显著提高了估计POD的能力（R2 = 0.51）。
