Department of Biology, Ege University, Bornova-Izmir, Turkey.
Lett Appl Microbiol. 2013 Mar;56(3):168-79. doi: 10.1111/lam.12028. Epub 2013 Jan 14.
In recent years, functional fabrics possessing antimicrobial activity have drawn significant interest because antibiotic resistance is becoming widespread among pathogenic micro-organisms. The aim of this study was to produce microcapsules incorporating ozonated red pepper seed oil (ORPSO) with antimicrobial properties and apply them to nonwoven fabrics to prepare functional textiles. Red pepper seed oil (RPSO) was ozonated and micro-encapsulated via a complex coacervation method using gelatin (GE) and gum arabic (GA) as wall materials. While micro-encapsulation yield and oil loading decreased with increases in the amount of surfactant, the mean particle size increased. The antimicrobial activity of the oil was tested via the disc diffusion method. The microcapsules were also tested using the agar well method. While RPSO had no effect on the test micro-organisms, the ORPSO and microcapsules containing ORPSO were found to be active against the test micro-organisms. The microcapsules were then applied to nonwoven fabric using the padding method to produce a disposable functional textile. The microcapsule-impregnated functional fabrics provided a 5 log decrease in 1 h. It is therefore possible to functionalize nonwoven fabrics to have antimicrobial activity against antibiotic-resistant micro-organisms, using microcapsules containing ORPSO.
This is the first report on the antimicrobial action of RPSO after ozonation process. These findings suggest that ozonated red pepper seed oil (ORPSO) may be a useful and effective antimicrobial agent against the micro-organisms with antibiotic resistance. Therefore, as a natural product, RPSO represents a sustainable alternative to the use of synthetic antimicrobial agents. To our knowledge, this is also the first time that ORPSO has been micro-encapsulated for the preparation of functional textile material with significant antimicrobial activity.
近年来，具有抗菌活性的功能面料引起了人们的极大兴趣，因为抗生素耐药性在致病微生物中越来越普遍。本研究旨在制备具有抗菌性能的臭氧处理红花椒籽油（ORPSO）微胶囊，并将其应用于非织造布制备功能性纺织品。红花椒籽油（RPSO）经臭氧处理后，采用明胶（GE）和阿拉伯胶（GA）作为壁材的复凝聚法进行微胶囊化。虽然微胶囊化产率和油载量随表面活性剂用量的增加而降低，但平均粒径增大。通过圆盘扩散法测试油的抗菌活性。采用琼脂井法对微胶囊进行测试。虽然 RPSO 对测试微生物没有影响，但发现 ORPSO 和含有 ORPSO 的微胶囊对测试微生物具有活性。然后采用浸渍法将微胶囊应用于非织造布，制备一次性功能纺织品。微胶囊浸渍的功能织物在 1 小时内提供了 5 个对数的减少。因此，使用含有 ORPSO 的微胶囊可以使非织造布具有抗菌活性，对抗抗生素耐药的微生物。
这是臭氧处理后 RPSO 抗菌作用的首次报道。这些发现表明，臭氧处理红花椒籽油（ORPSO）可能是一种对抗具有抗生素耐药性的微生物的有用且有效的抗菌剂。因此，作为一种天然产物，RPSO 代表了对抗生素类抗菌剂的可持续替代品。据我们所知，这也是首次将 ORPSO 微胶囊化用于制备具有显著抗菌活性的功能性纺织材料。
