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青少年边缘型人格特质情绪调节训练:一项随机对照试验。

Emotion regulation training for adolescents with borderline personality disorder traits: a randomized controlled trial.

机构信息

University Center of Child and Adolescent Psychiatry, Groningen, The Netherlands.

出版信息

J Am Acad Child Adolesc Psychiatry. 2012 Dec;51(12):1314-1323.e2. doi: 10.1016/j.jaac.2012.09.002. Epub 2012 Nov 8.

Abstract

OBJECTIVE

To evaluate the effectiveness of Emotion Regulation Training (ERT), a 17-session weekly group training for adolescents with borderline personality disorder (BPD) symptoms.

METHOD

One hundred nine adolescents with borderline traits (73% meeting the full criteria for BPD) were randomized to treatment as usual only (TAU) or ERT + TAU. Outcome measurements included severity of BPD symptoms, general psychopathology, and quality of life. Multilevel analyses were conducted on an intent-to-treat basis. Clinical significant change was determined by normative comparisons on a primary outcome measurement.

RESULTS

Independent of treatment condition, the two groups improved equally on the severity of BPD symptoms, general psychopathology, and quality of life. Nineteen percent of the ERT group was remitted according to the cutoff score after treatment (at 6 months) versus 12% of the control group. Follow-up assessments in the ERT group at 12 months showed some further improvement (33% remittance). With regard to predictors of outcomes, adolescents with higher levels of depression or attention-deficit/hyperactivity disorder or oppositional-defiant disorder at baseline and who reported a history of abuse had worse outcomes, regardless of treatment condition. The attrition rate for the ERT sessions was remarkably low (19%).

CONCLUSIONS

Early interventions for BPD symptoms in adolescence are feasible and necessary. No additional effect of ERT over TAU could be demonstrated in the present study. There is a clear need for developing effective interventions for adolescents with persistent BPD symptomatology. Clinical trial registration information-Evaluation of Group Training for Adolescents (Emotion Regulation Training) with Emotion Regulation Problems: A Randomized Controlled Clinical Trial; http://trailregister.nl/; ISRCTN97589104.

摘要

目的

评估情绪调节训练(ERT)的有效性,ERT 是一种针对边缘型人格障碍(BPD)症状的青少年的 17 次每周小组训练。

方法

109 名具有边缘特质的青少年(73%符合 BPD 的全部标准)被随机分为仅接受常规治疗(TAU)或 ERT+TAU。结果测量包括 BPD 症状严重程度、一般精神病理学和生活质量。采用多层次分析进行意向治疗。通过主要结果测量的规范比较来确定临床显著变化。

结果

无论治疗条件如何,两组在 BPD 症状严重程度、一般精神病理学和生活质量方面的改善程度都相同。ERT 组中有 19%的患者根据治疗后(6 个月)的截止分数达到缓解,而对照组为 12%。ERT 组在 12 个月的随访评估中显示出进一步的改善(33%缓解)。关于结局的预测因素,基线时抑郁或注意缺陷/多动障碍或对立违抗性障碍水平较高、有虐待史的青少年,无论治疗条件如何,结局都较差。ERT 课程的缺课率非常低(19%)。

结论

青少年 BPD 症状的早期干预是可行和必要的。本研究未显示 ERT 比 TAU 有额外的效果。对于持续性 BPD 症状的青少年,迫切需要开发有效的干预措施。临床试验注册信息-情绪调节问题的青少年团体训练(情绪调节训练)的评估:一项随机对照临床试验;http://trailregister.nl/;ISRCTN97589104。

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