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卵巢癌患者生活质量的纵向评估。

Longitudinal assessment of quality of life in ovarian cancer patients.

机构信息

Institute of Nursing and Health Sciences, Medical Department, University of Rzeszow, Rzeszow, Poland.

出版信息

Eur J Oncol Nurs. 2013 Jun;17(3):381-5. doi: 10.1016/j.ejon.2012.10.014. Epub 2012 Nov 29.

Abstract

OBJECTIVE

The objective of this work was to evaluate longitudinally the quality of life (QOL) in women treated for ovarian cancer, pre-operatively, three and six months postoperatively.

METHODS

A longitudinal cohort study. A total of 93 patients with newly diagnosed ovarian cancer in F. Chopin Voivodeship Specialist Hospital in Rzeszow, Poland were interviewed pre- and post-operatively with two questionnaires: EORTC QLQ-C30 and QLQ- OV28 between October 2006 and December 2008.

RESULTS

Based on EORTC QLQ-30 it was found that global health and emotional functioning improved. An improvement regarding symptoms such as nausea and vomiting was recorded between T2 and T3. Patients complained less of pain in the whole studied period of time. Based on the modules of the QLQ-OV28 showed improvement of QOL on the scales concerning abdominal and attitude to disease/treatment. Decrease of symptoms on the scales concerning body image and sexual worries were observed. Increase of chemotherapy side effects and hormonal symptoms were observed between T1 and T2, but then improved.

CONCLUSIONS

QOL of patients had increased after the treatment in comparison to the baseline. There is a need to implement the assessment of quality of life in ovarian cancer patients in practice.

摘要

目的

本研究旨在评估接受卵巢癌治疗的女性在术前、术后 3 个月和 6 个月的生活质量(QOL)。

方法

这是一项纵向队列研究。2006 年 10 月至 2008 年 12 月期间,对波兰热舒夫 F.肖邦地区专科医院的 93 例新诊断为卵巢癌的患者进行了术前和术后两次问卷调查:EORTC QLQ-C30 和 QLQ-OV28。

结果

基于 EORTC QLQ-30,发现总体健康状况和情绪功能有所改善。T2 和 T3 之间记录到恶心和呕吐等症状有所改善。在整个研究期间,患者的疼痛减轻。基于 QLQ-OV28 的模块,在涉及腹部和对疾病/治疗的态度的量表上观察到 QOL 的改善。在身体形象和性担忧方面的症状减轻。在 T1 和 T2 之间观察到化疗副作用和激素症状的增加,但随后有所改善。

结论

与基线相比,治疗后患者的生活质量有所提高。需要在实践中实施对卵巢癌患者生活质量的评估。

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