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地中海纬度地区的紫外线辐射与人工晶状体的防护效果

Ultraviolet radiation at Mediterranean latitudes and protection efficacy of intraocular lenses.

作者信息

Artigas J M, Felipe A, Navea A, Artigas C, Menezo J L

机构信息

Fundación oftalmológica del Mediterráneo (FOM), bifurcación Pío Baroja-General Avilés, s/n. E46015 Valencia, Spain.

出版信息

J Fr Ophtalmol. 2013 Jan;36(1):23-8. doi: 10.1016/j.jfo.2012.03.018. Epub 2012 Nov 30.

DOI:10.1016/j.jfo.2012.03.018
PMID:23201342
Abstract

PURPOSE

After determining the mean intensity of ultraviolet radiation to which the human eye is exposed at Mediterranean latitudes, this data is used to evaluate the efficacy of the ultraviolet filters incorporated into various intraocular lenses.

METHODS

Ultraviolet radiation measured at Mediterranean latitudes was used as a reference for the theoretical calculation of the amount of radiation to which the human eye is exposed. The spectral transmission curve from 290 to 380 nm was measured for 10 IOLs using a UV/VIS Perkins-Elmer Lambda 800 spectrometer.

RESULTS

At Mediterranean latitudes, at sea level, with a mean annual solar irradiation of 50 j/cm(2), the human eye receives a quantity of UVA and UVB that is lower than the threshold toxic dose for the rabbit crystalline lens (93 j/cm(2) for UVA and 6.45 j/cm(2) for UVB). However, at higher altitudes and with albedo approaching 0.9 (fresh snow), the amount of radiation increases, with duration of exposure potentially playing a significant role. The UV filters incorporated into the IOLs studied are, in general, protective against such levels of radiation.

CONCLUSION

At Mediterranean latitudes, at sea level, the amount of UV radiation to which our eyes are exposed is insufficient to damage the crystalline lens; however, at higher altitudes, the risk of such damage exists. UV filters incorporated into intraocular lenses are generally effective, since they filter all radiation with wavelengths under 380 nm.

摘要

目的

在确定了地中海纬度地区人眼所暴露的紫外线平均强度后,利用该数据评估各种人工晶状体中所含紫外线滤光片的功效。

方法

以在地中海纬度地区测量的紫外线辐射作为人眼所暴露辐射量理论计算的参考。使用紫外/可见珀金埃尔默Lambda 800光谱仪测量了10种人工晶状体从290至380纳米的光谱透射曲线。

结果

在地中海纬度地区海平面上,年平均太阳辐照量为50焦耳/平方厘米时,人眼接收到的紫外线A和紫外线B量低于兔晶状体的阈毒性剂量(紫外线A为93焦耳/平方厘米,紫外线B为6.45焦耳/平方厘米)。然而,在更高海拔且反照率接近0.9(新雪)时,辐射量增加,暴露持续时间可能起重要作用。所研究的人工晶状体中所含的紫外线滤光片总体上能防护此类辐射水平。

结论

在地中海纬度地区海平面上,我们眼睛所暴露的紫外线量不足以损害晶状体;然而,在更高海拔地区,存在这种损害的风险。人工晶状体中所含的紫外线滤光片通常是有效的,因为它们能滤除波长低于380纳米的所有辐射。

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