Ross Tilley Burn Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, M4N 3M5, Canada.
Nutrients. 2012 Oct 29;4(11):1554-65. doi: 10.3390/nu4111554.
Failure to adequately address the increased levels of inflammatory mediators, catecholamines and corticosteroids central to the hypermetabolic response post burn injury can lead to catastrophic results. One of the most important perturbations is provision of adequate and early nutrition. The provision of the right balance of macro and micronutrients, along with additional antioxidants is essential to mitigating the hypermetabolic and hypercatabolic state that results following a burn injury. As it is now widely accepted that enteral feeding is best practice for the burn population research has been more closely examining the individual components of enteral nutrition support. Recently fat to carbohydrate ratios, glutamine and antioxidants have made up the balance of this focus. This paper provides a review of the most recent literature examining each of these components and discusses the practices adopted in the Ross Tilley Burn Centre at Sunnybrook Health Sciences Centre.
未能充分解决烧伤后高代谢反应中核心的炎症介质、儿茶酚胺和皮质类固醇水平的升高,可能导致灾难性的后果。最重要的干扰之一是提供充足和早期的营养。提供宏量和微量营养素的正确平衡,以及额外的抗氧化剂,对于减轻烧伤后导致的高代谢和高分解状态至关重要。由于现在广泛接受肠内喂养是烧伤患者的最佳实践,因此研究更加密切地关注肠内营养支持的各个组成部分。最近,脂肪与碳水化合物的比例、谷氨酰胺和抗氧化剂已成为这一重点的平衡。本文综述了最近检查这些成分的文献,并讨论了在多伦多 Sunnybrook 健康科学中心 Ross Tilley 烧伤中心采用的做法。