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流行引发的麻痹:以甲状腺毒症性周期性麻痹形式出现的隐匿性格雷夫斯病

Pop-provoked paralysis: silent Graves' disease presenting as thyrotoxic periodic paralysis.

作者信息

Sehmer Benjamin, Arnason Terra

机构信息

Department of Internal Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.

出版信息

BMJ Case Rep. 2012 Nov 30;2012:bcr2012006292. doi: 10.1136/bcr-2012-006292.

Abstract

A 48-year-old Filipino man presented after several episodes of worsening limb paralysis that occurred after drinking cola beverages. In the emergency department he was found to be hypokalaemic, and although he exhibited no symptoms of thyrotoxicosis he was biochemically hyperthyroid. Thyroid stimulating hormone receptor antibody serology was positive indicating Graves' disease as the underlying cause of his hyperthyroidism. Intravenous potassium supplementation resulted in complete resolution of symptoms, and a diagnosis of thyrotoxic periodic paralysis was made. He was started on a regimen of propylthiouracil and propranolol and subsequently given radioiodine as the definitive treatment for Graves' disease. There were no recurrent attacks of paralysis once a stable euthyroid state was achieved, and the patient was able to resume cola consumption without issue.

摘要

一名48岁的菲律宾男子在饮用可乐饮料后出现数次肢体麻痹加重的情况后前来就诊。在急诊科,发现他血钾过低,尽管他没有甲状腺毒症的症状,但生化检查显示甲状腺功能亢进。促甲状腺激素受体抗体血清学检查呈阳性,表明格雷夫斯病是其甲状腺功能亢进的根本原因。静脉补充钾后症状完全缓解,诊断为甲状腺毒症性周期性麻痹。他开始接受丙硫氧嘧啶和普萘洛尔治疗,随后接受放射性碘作为格雷夫斯病的确定性治疗。一旦达到稳定的甲状腺功能正常状态,就没有再次出现麻痹发作,患者能够毫无问题地继续饮用可乐。

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