Andreasson S, Allebeck P, Romelsjö A
Department of Social Medicine, Karolinska Institute, Huddinge University Hospital, Sweden.
Br Med J (Clin Res Ed). 1988 Apr 9;296(6628):1021-5. doi: 10.1136/bmj.296.6628.1021.
The association between alcohol consumption and 15 year mortality was studied in a cohort of 49,464 Swedish conscripts, mostly aged 18-19. A strong association was found. The relative risk of death among conscripts with a high consumption of alcohol (greater than 250 g/week) was 3.0 (95% confidence interval (2.3 to 4.1) compared with those with moderate consumption (1-100 g/week). After adjustment for social background variables the relative risk was reduced to 2.1 (95% confidence interval 1.4 to 3.2). Among causes of death a strong predominance was found for violent death, suicide or probable suicide being the leading single cause and accounting for 236 (36%) of all deaths. The reported U shaped curve for total mortality was not confirmed, though when violent deaths were excluded a U shaped curve was suggested for other causes of death. These findings provide important epidemiological data on the drinking habits of young people and the consequences for mortality.
在一个由49464名瑞典应征入伍者组成的队列中,研究了饮酒与15年死亡率之间的关联,这些应征者大多年龄在18至19岁。研究发现了一种强烈的关联。与中度饮酒者(每周1 - 100克)相比,高酒精摄入量(每周超过250克)的应征者的死亡相对风险为3.0(95%置信区间为2.3至4.1)。在对社会背景变量进行调整后,相对风险降至2.1(95%置信区间为1.4至3.2)。在死因方面,暴力死亡占主导地位,自杀或疑似自杀是主要的单一死因,占所有死亡人数的236例(36%)。尽管排除暴力死亡后,其他死因的死亡率呈现U形曲线,但总死亡率的U形曲线并未得到证实。这些发现提供了关于年轻人饮酒习惯及其对死亡率影响的重要流行病学数据。