State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing 210023, People's Republic of China.
Chemosphere. 2013 Feb;90(7):2123-8. doi: 10.1016/j.chemosphere.2012.10.095. Epub 2012 Dec 1.
The estrogenic activities of source water from Yangtze River, Huaihe River, Taihu Lake and groundwater in Yangtze River Delta in the dry and wet season were determined by use of reporter gene assays based on African green monkey kidney (CV-1) cell lines. Higher estrogenic activities were observed in the dry season, and the estrogenic potentials in water samples from Taihu Lake were greater than other river basins. None of the samples from groundwater showed estrogen receptor (ER) agonist activity. The 17β-Estradiol (E2) equivalents (EEQs) of water samples in the dry season ranged from 9.41×10(-1) to 1.20×10(1) ng E2 L(-1). In the wet season, EEQs of all the water samples were below the detection limit as 9.00×10(-1) ng E2 L(-1) except for one sample from Huaihe River. The highest contribution of E2 was detected in Yangtze River as 99% of estrogenic activity. Nonylphenol (NP, 100% detection rate) and octylphenol (OP, 100% detection rate) might also be responsible for the estrogenic activities in water sources. Potential health risk induced by the estrogenic chemicals in source water may be posed to the residents through water drinking.
采用基于非洲绿猴肾（CV-1）细胞系的报告基因检测方法，测定了长江、淮河、太湖水源和长江三角洲地区地下水枯水期和丰水期的雌激素活性。枯水期水样的雌激素活性较高，太湖水样的雌激素潜力大于其他流域。地下水水样均未表现出雌激素受体（ER）激动剂活性。枯水期水样的 17β-雌二醇（E2）当量（EEQ）范围为 9.41×10(-1)至 1.20×10(1)ng E2 L(-1)。丰水期，除了淮河的一个水样外，所有水样的 EEQ 均低于检测限 9.00×10(-1)ng E2 L(-1)。长江水样中 E2 的贡献最高，占雌激素活性的 99%。壬基酚（NP，检出率 100%）和辛基酚（OP，检出率 100%）也可能是水源中雌激素活性的原因。通过饮用水，水源中雌激素类化学物质可能会对居民造成潜在的健康风险。
