Leibniz Institute for Zoo and Wildlife Research, Alfred-Kowalke-Str. 17, 10315, Berlin, Germany.
Arch Virol. 2013 Apr;158(4):729-34. doi: 10.1007/s00705-012-1562-x. Epub 2012 Dec 5.
Knowledge of coronaviruses in wild carnivores is limited. This report describes coronavirus genetic diversity, species specificity and infection prevalence in three wild African carnivores. Coronavirus RNA was recovered from fresh feces from spotted hyena and silver-backed jackal, but not bat-eared fox. Analysis of sequences of membrane (M) and spike (S) gene fragments revealed strains in the genus Alphacoronavirus, including three distinct strains in hyenas and one distinct strain in a jackal. Coronavirus RNA prevalence was higher in feces from younger (17 %) than older (3 %) hyenas, highlighting the importance of young animals for coronavirus transmission in wild carnivores.
野生食肉动物中的冠状病毒知识有限。本报告描述了三种野生非洲食肉动物中冠状病毒的遗传多样性、物种特异性和感染流行情况。从斑点鬣狗和银背胡狼的新鲜粪便中回收了冠状病毒 RNA，但在蝠耳狐中未检测到。对膜（M）和刺突（S）基因片段序列的分析显示，该属中存在α冠状病毒株，包括在鬣狗中有三种不同的株，在胡狼中有一个不同的株。在较年轻（17%）的鬣狗粪便中冠状病毒 RNA 的流行率高于较年长（3%）的鬣狗，这突出表明了年轻动物在野生食肉动物中传播冠状病毒的重要性。
