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[使用Scheimpflug HR成像系统、激光干涉测量法、自动角膜曲率计和超声测厚法比较中央角膜厚度和角膜曲率测量结果]

[Comparison of central corneal thickness and keratometric measurements using the Scheimpflug HR imaging system, laser interferometry, automatic keratometry and ultrasound pachymetry].

作者信息

Pašová P, Skorkovská K, Michálek J

机构信息

Zilinske ocne centrum VIKOM, Zilina.

出版信息

Cesk Slov Oftalmol. 2012 Jul;68(3):116-9.

PMID:23214460
Abstract

INTRODUCTION

The aim of our study was to compare keratometry and central corneal thickness measurements obtained with three different ophthalmic devices and to decide if they can be used interchangeably in clinical practice.

METHODS

43 healthy persons were included in the study (29 women and 14 men, average age 25 ± 3.5 years). Central corneal thickness (CCT) was measured with the Scheimpflug HR imaging system (Pentacam), Allegro BioGraph and with ultrasound pachymetry (RXP OcuScan). Keratometry in two main meridians of the cornea (K1, K2) was measured with Pentacam, Allegro BioGraph and automated keratometry.

RESULTS

The mean difference in K1-readings was 0.01 ± 0.31 D for BioGraph vs. automated keratometry, 0.06 ± 0.23 D for BioGraph vs. Pentacam and 0.05 ± 0.34 D for automated keratometry and Pentacam. The mean difference in K2-readings was 0.29 ± 0.45 D for BioGraph vs. automated keratometry, 0.11 ± 0.28 D for BioGraph vs. Pentacam and 0.19 ± 0.44 D for automated keratometry and Pentacam. The interdevice differences were in all cases statistically significant (p < 0.05). The mean difference in CCT was 4.57 ± 7.84 μm for BioGraph vs. ultrasound, 4.33 ± 7.55 μm for BioGraph vs. Pentacam and 8.90 ± 7.49 μm for ultrasound vs. Pentacam. The interdevice differences in CCT were also statistically significant (p < 0.05).

CONCLUSION

Our results suggest that the measurements of keratometry and CCT may differ significantly between the tested machines and therefore should not be used interchangeably in clinical practice.

摘要

引言

我们研究的目的是比较使用三种不同眼科设备获得的角膜曲率测量值和中央角膜厚度测量值,并确定它们在临床实践中是否可以互换使用。

方法

43名健康人纳入本研究(29名女性和14名男性,平均年龄25±3.5岁)。使用眼前节分析系统(Pentacam)、Allegro BioGraph和超声角膜测厚仪(RXP OcuScan)测量中央角膜厚度(CCT)。使用Pentacam、Allegro BioGraph和自动角膜曲率计测量角膜两个主要子午线方向的角膜曲率(K1、K2)。

结果

BioGraph与自动角膜曲率计之间K1读数的平均差值为0.01±0.31D,BioGraph与Pentacam之间为0.06±0.23D,自动角膜曲率计与Pentacam之间为0.05±0.34D。BioGraph与自动角膜曲率计之间K2读数的平均差值为0.29±0.45D,BioGraph与Pentacam之间为0.11±0.28D,自动角膜曲率计与Pentacam之间为0.19±0.44D。所有情况下,不同设备间的差异均具有统计学意义(p<0.05)。BioGraph与超声角膜测厚仪之间CCT的平均差值为4.57±7.84μm,BioGraph与Pentacam之间为4.33±7.55μm,超声角膜测厚仪与Pentacam之间为8.90±7.49μm。不同设备间CCT的差异也具有统计学意义(p<0.05)。

结论

我们的结果表明,在测试的仪器之间,角膜曲率测量值和CCT测量值可能存在显著差异,因此在临床实践中不应互换使用。

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