Department of Ophthalmology, Saglik Bilimleri University Fatih Sultan Mehmet Training and Research Hospital, 34752, Istanbul, Turkey.
Department of Ophthalmology, Hisar Intercontinental Hospital, 34768, Istanbul, Turkey.
Int Ophthalmol. 2021 May;41(5):1659-1669. doi: 10.1007/s10792-021-01720-5. Epub 2021 Feb 5.
To determine agreement in keratometric readings obtained using rotating Scheimpflug imaging with Pentacam, biograph with Lenstar LS900, and Topcon KR-8100P auto-keratorefractometer in eyes with different stages of keratoconus.
A total of 89 eyes of 58 patients with keratoconus were examined in this study, retrospectively. The eyes were divided into two groups: mild group (group 1: 42 eyes) (Amsler-Krumeich stage 1) and moderate-to-severe group (group 2: 47 eyes) (Amsler-Krumeich stage 2, 3, 4). The keratometric readings measured using the Pentacam Scheimpflug system, Lenstar LS900, and Topcon KR-8100P auto-keratorefractometer were compared between the groups. The effects of the measurements of anterior chamber depth, Q value, axial length, central corneal thickness (CCT), and maximum value of keratometry (Kmax) on the differences of devices for keratometric readings were investigated.
The mean values of the keratometric readings obtained using the Lenstar were steeper than with the Pentacam and Topcon, especially in group 2. In group 1, the mean K2 values measured using the Lenstar were significantly steeper than with the Topcon (p < 0.05); however, the devices were accordant for the other keratometric readings. In group 2, there was an agreement between the Pentacam and Topcon for the mean K1 and Km values; however, there were significant differences between the devices for the other values. The Q value and CCT had a negative correlation, and Kmax had a positive correlation with the differences of Lenstar-Pentacam and Lenstar-Topcon (p < 0.01).
According to our results, Pentacam-Topcon and Pentacam-Lenstar can be used interchangeably for keratometry in mild stages of keratoconus. The keratometric readings of Lenstar were found steeper than the other devices with increasing grades of keratoconus. None of these devices can be used interchangeably in moderate-to-severe stages of keratoconus.
确定在不同阶段圆锥角膜眼中使用旋转式 Scheimpflug 成像 Pentacam、biograph 与 Lenstar LS900 以及 Topcon KR-8100P 自动角膜曲率计获得的角膜曲率读数的一致性。
本研究回顾性分析了 58 例 89 只圆锥角膜眼，将这些眼分为两组：轻度组（第 1 组：42 只眼）（Amsler-Krumeich 1 期）和中重度组（第 2 组：47 只眼）（Amsler-Krumeich 2、3、4 期）。比较了 Pentacam Scheimpflug 系统、Lenstar LS900 和 Topcon KR-8100P 自动角膜曲率计测量的角膜曲率读数。研究了前房深度、Q 值、眼轴长度、中央角膜厚度（CCT）和最大角膜曲率（Kmax）测量值对设备间角膜曲率读数差异的影响。
Lenstar 测量的角膜曲率平均值比 Pentacam 和 Topcon 更陡峭，尤其是在第 2 组。在第 1 组中，Lenstar 测量的平均 K2 值明显比 Topcon 陡峭（p<0.05）；然而，其他角膜曲率读数时设备是一致的。在第 2 组中，Pentacam 和 Topcon 之间的平均 K1 和 Km 值具有一致性；然而，其他值时设备之间存在显著差异。Q 值和 CCT 呈负相关，Kmax 与 Lenstar-Pentacam 和 Lenstar-Topcon 之间的差异呈正相关（p<0.01）。
根据我们的结果，在圆锥角膜的轻度阶段，Pentacam-Topcon 和 Pentacam-Lenstar 可相互替代用于角膜曲率测量。随着圆锥角膜等级的增加，Lenstar 的角膜曲率读数比其他设备更陡峭。在圆锥角膜的中重度阶段，这些设备均不可相互替代。
