Health Protection Agency South West Regional Epidemiology Unit, UK.
Epidemiol Infect. 2013 Oct;141(10):2043-50. doi: 10.1017/S0950268812002816. Epub 2012 Dec 6.
In August 2011, we investigated an outbreak of Escherichia coli O157 in Plymouth, England, utilizing a case-control study and food traceback. Nine cases, eight laboratory-confirmed with E. coli O157 phage type 21/28 verocytotoxin 2 and one epidemiologically linked, had onsets from 30 July 2011 to 15 August 2011. We compared cases (n=8) with controls (n=28) of similar age and sex (median age 61 vs. 55 years, females 75% vs. 61%). Cases were 58 times more likely to have eaten crab (88% vs. 11%; odds ratio 58, 95% confidence interval 4-2700). Eight cases consumed crab sourced from the same supplier who was not registered with the local authority. This outbreak pointed to crab as a possible vehicle of E. coli O157 infection. We ensured the withdrawal of crab meat sourced from unregistered suppliers from food venues by 25 August 2011. We also emphasized the importance of only using registered suppliers to the food venues. Since then no further associated cases have been reported.
2011 年 8 月，我们采用病例对照研究和食品溯源的方法，调查了英格兰普利茅斯的一起大肠杆菌 O157 暴发事件。9 例病例中有 8 例经实验室确认为大肠杆菌 O157 噬菌体型 21/28 肠毒素 2，1 例具有流行病学关联，发病时间为 2011 年 7 月 30 日至 8 月 15 日。我们将 8 例病例（年龄和性别与对照组相似，中位数年龄为 61 岁比 55 岁，女性占 75%比 61%）与 28 例对照组进行了比较。病例组食用蟹的可能性是对照组的 58 倍（88%比 11%；比值比 58，95%置信区间 4-2700）。8 例病例食用的蟹均来自未在当地主管部门登记的同一供应商。此次暴发事件表明，蟹可能是大肠杆菌 O157 感染的一个潜在载体。我们于 2011 年 8 月 25 日确保从无注册供应商处撤回供餐场所的蟹肉。我们还强调了仅使用注册供应商向食品场所供应食物的重要性。自那以后，没有再报告相关病例。
