Unité END (Endocrinologie, Nutrition, Diabétologie), CHRU Bretonneau, 37044 Tours cedex 9, France.
Diabetes Metab. 2013 Apr;39(2):139-47. doi: 10.1016/j.diabet.2012.10.004. Epub 2012 Dec 4.
This study estimated the prevalence of symptoms evocative of obstructive sleep apneoa (OSA) in patients with type 2 diabetes and the proportion of those with evidence of a previous diagnosis or diagnostic procedure.
In ENTRED 2007, 8926 people reimbursed for at least three antidiabetic agents within the last 12 months were randomly selected, and 3894 answered a self-administered questionnaire. Symptoms evocative of OSA were defined as frequent snoring with excessive daytime sleepiness and/or witnessed sleep apneoa. Patients were considered to have evidence of a previous diagnostic procedure if they reported an OSA diagnosis or had a sleep recording done, or if a sleep recording was found in the hospital discharge or medical claims database, or if they were currently being treated with nocturnal ventilation.
The patients' mean age was 66 years. Around 8.5% reported being diagnosed with OSA, 4.2% were treated with nocturnal ventilation and 16% had symptoms evocative of OSA. Being male, obesity, high blood pressure, insulin treatment, living with a partner, lower educational level and financial difficulties were all associated with symptoms suggestive of OSA. Overall, 13% had evidence of a previous diagnostic procedure, and the rate was 35% among those with symptoms evocative of OSA.
OSA is underdiagnosed in French diabetic patients, while the prevalence of symptoms is high. Only 13% of the study population and 35% of those with symptoms suggestive of OSA had benefited from a diagnostic procedure. It is of the utmost importance to better diagnose OSA in the diabetic population.
本研究旨在评估 2 型糖尿病患者中存在阻塞性睡眠呼吸暂停(OSA)症状的比例,并评估有过诊断或诊断性检查的患者比例。
在 ENTRED 2007 研究中,随机抽取了 8926 名过去 12 个月内至少使用过三种降糖药物的患者,其中 3894 名患者回答了一份自填问卷。OSA 症状包括频繁打鼾、白天过度嗜睡和/或观察到的睡眠呼吸暂停。如果患者报告有 OSA 诊断、进行过睡眠记录或在医院出院或医疗记录数据库中发现睡眠记录、或正在接受夜间通气治疗,则认为他们有过诊断性检查。
患者的平均年龄为 66 岁。约 8.5%的患者报告被诊断为 OSA,4.2%的患者接受夜间通气治疗,16%的患者有 OSA 症状。男性、肥胖、高血压、胰岛素治疗、与伴侣同住、较低的教育程度和经济困难均与 OSA 症状相关。总的来说,有 13%的患者有过诊断性检查,有 OSA 症状的患者中这一比例为 35%。
法国糖尿病患者的 OSA 诊断不足,而症状的患病率较高。仅 13%的研究人群和 35%的有 OSA 症状的患者接受了诊断性检查。对糖尿病患者进行 OSA 的诊断至关重要。