利用平板电子射野影像装置进行多平面剂量验证用于调强放射治疗的研究进展

Development of multi-planar dose verification by use of a flat panel EPID for intensity-modulated radiation therapy.

作者信息

Nakaguchi Yuji, Araki Fujio, Kouno Tomohiro, Ono Takeshi, Hioki Kazunari

机构信息

Department of Radiological Technology, Kumamoto University Hospital, 1-1-1 Honjyo, Kumamoto, Japan.

出版信息

Radiol Phys Technol. 2013 Jan;6(1):226-32. doi: 10.1007/s12194-012-0192-z. Epub 2012 Dec 11.

DOI:10.1007/s12194-012-0192-z

PMID:23229201

Abstract

Our purpose in this study was to evaluate the accuracy of a new multi-planar dose measurement method. The multi-planar dose distributions were reconstructed at each depth by convolution of EPID fluence and dose kernels with the use of EPIDose software (SunNuclear). The EPIDose was compared with EPID, MapCHECK (SunNuclear), EDR2 (Kodak), and Monte Carlo-calculated dose profiles. The EPIDose profiles were almost in agreement with Monte Carlo-calculated dose profiles and MapCHECK for test plans. The dose profiles were in good agreement with EDR2 at the penumbra region. For dose distributions, EPIDose, EDR2, and MapCHECK agreed with that of the treatment-planning system at each depth in the gamma analysis. In comparisons of clinical IMRT plans, EPIDose had almost the same accuracy as MapCHECK and EDR2. Because EPIDose has a wide dynamic range and high resolution, it is a useful tool for the complicated IMRT verification. Furthermore, EPIDose can also evaluate the absolute dose.

摘要

本研究的目的是评估一种新的多平面剂量测量方法的准确性。使用EPIDose软件（SunNuclear）通过对电子射野影像装置（EPID）注量和剂量核进行卷积，在每个深度重建多平面剂量分布。将EPIDose与EPID、MapCHECK（SunNuclear）、EDR2（柯达）以及蒙特卡洛计算的剂量剖面进行比较。对于测试计划，EPIDose剖面与蒙特卡洛计算的剂量剖面以及MapCHECK几乎一致。在半影区，剂量剖面与EDR2吻合良好。对于剂量分布，在伽马分析中，EPIDose、EDR2和MapCHECK在每个深度均与治疗计划系统的剂量分布一致。在临床调强放射治疗（IMRT）计划的比较中，EPIDose的准确性与MapCHECK和EDR2几乎相同。由于EPIDose具有宽动态范围和高分辨率，它是复杂IMRT验证的有用工具。此外，EPIDose还可以评估绝对剂量。