P Stradins Clinical University Hospital, Riga, Latvia.
Antimicrob Agents Chemother. 2013 Feb;57(2):1069-72. doi: 10.1128/AAC.01783-12. Epub 2012 Dec 10.
An outbreak of hospital-acquired Acinetobacter baumannii infections, caused by a bla(OXA-23)-positive carbapenem-resistant strain belonging to international clone II/ST2, was detected in Latvia. The strain was partially equipped with the armA gene and the intI1-aacA4-catB8-aadA1-qacEΔ1 class 1 integron. In addition, the strain carried AbaR25, a novel AbaR4-like resistance island of ~46,500 bp containing structures similar to the previously described AbaR22 and Tn6167 islands. AbaR25 was characterized by the occurrence of a second copy of Tn6022a interrupted by Tn2006 carrying the bla(OXA-23) gene.
在拉脱维亚检测到一起由一株bla(OXA-23)-阳性碳青霉烯类耐药的鲍曼不动杆菌医院感染暴发事件，该菌株属于国际克隆 II/ST2。该菌株部分配备了 armA 基因和 intI1-aacA4-catB8-aadA1-qacEΔ1 类 1 整合子。此外，该菌株还携带 AbaR25，这是一个约 46500bp 的新型 AbaR4 样耐药岛，包含与先前描述的 AbaR22 和 Tn6167 岛相似的结构。AbaR25 的特征是出现第二个 Tn6022a 拷贝，该拷贝被携带 bla(OXA-23)基因的 Tn2006 中断。
