Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Invest Ophthalmol Vis Sci. 2013 Jan 9;54(1):280-7. doi: 10.1167/iovs.12-10657.
To propose a general conversion approximation algorithm and illustrate its application to two cataract classification systems, the Lens Opacity Classification System III (LOCS III) and Wisconsin Cataract Grading System (Wisconsin system).
Lens opacity of 3265 participants (78.7% response rate) aged 40 to 80 years from the Singapore Malay Eye study were assessed both clinically during slit-lamp examination using LOCS III, and via slit-lamp and retro-illumination photographic grading using the Wisconsin system. Collapsed contingency tables were used to convert between the LOCS III and Wisconsin System.
The conversion between the two cataract classification systems is affected by the direction of transformation. The conversion algorithm was validated and explained with an application example.
An approximate conversion algorithm for any two cataract grading systems was proposed and applied to the LOCS III and Wisconsin system. These findings provide general ways to pool and compare cataract prevalence using different grading systems in epidemiological studies.
提出一种通用的转换近似算法,并将其应用于两种白内障分类系统,即 Lens Opacity Classification System III(LOCS III)和 Wisconsin Cataract Grading System(威斯康星系统)。
对来自新加坡马来人眼研究的 3265 名 40 至 80 岁参与者(78.7%的应答率)的晶状体混浊度进行临床评估,使用 LOCS III 通过裂隙灯检查,以及使用威斯康星系统通过裂隙灯和背面照明摄影分级进行评估。使用折叠列联表在 LOCS III 和威斯康星系统之间进行转换。
两种白内障分类系统之间的转换受转换方向的影响。验证并通过应用示例解释了转换算法。
提出了一种用于任何两种白内障分级系统的近似转换算法,并将其应用于 LOCS III 和威斯康星系统。这些发现为使用不同分级系统在流行病学研究中汇总和比较白内障患病率提供了一般方法。