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黄烷酮：来源于红树林内生真菌黄曲霉 PSU-MA201 的一种新的二呋喃甲烷衍生物。

Flavodonfuran: a new difuranylmethane derivative from the mangrove endophytic fungus Flavodon flavus PSU-MA201.

机构信息

a Department of Chemistry and Center of Excellence for Innovation in Chemistry , Faculty of Science, Prince of Songkla University , Hat Yai Songkhla 90112 , Thailand.

出版信息

Nat Prod Res. 2013;27(19):1722-6. doi: 10.1080/14786419.2012.750315. Epub 2012 Dec 13.

DOI:10.1080/14786419.2012.750315
PMID:23234367
Abstract

One new difuranylmethane derivative, flavodonfuran (1), together with tremulenolide A (2) was isolated from the mangrove-derived fungus Flavodon flavus PSU-MA201.The difuranylmethane derivative based on 1 is rare in natural products. Their structures were established by spectroscopic evidence. Compound 2 exhibited mild antibacterial and antifungal activities against Staphylococcus aureus ATCC25923 and Cryptococcus neoformans ATCC90113, respectively.

摘要

从红树林来源的真菌 Flavodon flavus PSU-MA201 中分离到一个新的二呋喃甲 烷衍生物，flavodonfuran（1），以及 tremulenolide A（2）。基于 1 的二呋喃甲 烷衍生物在天然产物中较为罕见。它们的结构通过光谱证据确定。化合物 2 对金黄色葡萄球菌 ATCC25923 和新型隐球菌 ATCC90113 表现出温和的抗菌和抗真菌活性。

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