Chen Liang-Liang, Wang Pei, Chen Hui-Qin, Guo Zhi-Kai, Wang Hao, Dai Hao-Fu, Mei Wen-Li
Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.
Molecules. 2017 Feb 9;22(2):261. doi: 10.3390/molecules22020261.
Six new furan derivatives, named 5-(3-methoxy-3-oxopropyl)-furan-2-carboxylic acid (), 1-(5-(2-hydroxypropanoyl)-furan-2-yl)-pentan-3-one (), 2-hydroxy-1-(5-(1-hydroxypentyl)-furan-2-yl)-propan-1-one (), 1-(5-(1,2-dihydroxypropyl)-furan-2-yl)-pentan-1-one (), 5-(1-hydroxypent-4-en-1-yl)-furan-2-carboxylic acid () and 5-(3-hydroxypentyl)-furan-2-carboxylic acid (), together with two new natural products, named 5-(1-hydroxypentyl)-furan-2-carboxylic acid () and ()-5-(2-carboxyvinyl)-furan-2-carboxylic acid (), were isolated from the solid rice fermentation of endophytic fungus sp. J5, which was derived from mangrove plant . Their structures were unambiguously elucidated based on 1D and 2D NMR spectroscopy, and by HRESIMS measurements, as well as by comparison with the literature.
从源自红树林植物的内生真菌J5的固体大米发酵物中分离出六种新的呋喃衍生物，分别为5-(3-甲氧基-3-氧代丙基)-呋喃-2-羧酸（）、1-(5-(2-羟基丙酰基)-呋喃-2-基)-戊-3-酮（）、2-羟基-1-(5-(1-羟基戊基)-呋喃-2-基)-丙-1-酮（）、1-(5-(1,2-二羟基丙基)-呋喃-2-基)-戊-1-酮（）、5-(1-羟基戊-4-烯-1-基)-呋喃-2-羧酸（）和5-(3-羟基戊基)-呋喃-2-羧酸（），以及两种新的天然产物，分别为5-(1-羟基戊基)-呋喃-2-羧酸（）和()-5-(2-羧基乙烯基)-呋喃-2-羧酸（）。基于一维和二维核磁共振光谱、高分辨电喷雾电离质谱测量以及与文献对比，明确解析了它们的结构。
