Wormald R, Foster A
Department of Preventive Ophthalmology, Institute of Ophthalmology, London.
Eye (Lond). 1990;4 ( Pt 1):107-14. doi: 10.1038/eye.1990.13.
Of 34 consecutive patients with chronic glaucoma seen in north-east Ghana, 22 (65%) were male and seven (21%) were aged under 40 years. Only 17% of eyes had a visual acuity better than 6/18 at presentation. Sixteen of 23 patients who underwent gonioscopy had PAS of which 13 had positive skin snips for onchocerciasis, compared with two out of seven patients with positive skin snips who had open angle glaucoma (p = 0.003). Of 22 trabecular meshworks examined by light microscopy ten (45%) showed marked melanin pigmentation which was more common in younger patients but did not correlate with onchocerciasis infection.
在加纳东北部连续就诊的34例慢性青光眼患者中，22例（65%）为男性，7例（21%）年龄在40岁以下。初诊时仅17%的患眼视力优于6/18。接受前房角镜检查的23例患者中有16例存在周边前粘连，其中13例皮肤活检丝虫病阳性，而7例皮肤活检阳性的开角型青光眼患者中有2例（p = 0.003）。在22个经光学显微镜检查的小梁网中，10个（45%）显示有明显的黑色素沉着，这在年轻患者中更常见，但与盘尾丝虫病感染无关。
