Durmuş B, Arends L R, Ay L, Hokken-Koelega A C, Raat H, Hofman A, Steegers E A P, Jaddoe V W V
The Generation R Study Group, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Pediatrics, Erasmus Medical Center, Rotterdam, The Netherlands.
Pediatr Obes. 2013 Oct;8(5):339-50. doi: 10.1111/j.2047-6310.2012.00114.x. Epub 2012 Dec 13.
There are limited data regarding the associations of both maternal and paternal anthropometrics with longitudinally measured post-natal growth measures in early childhood.
To assess the associations of maternal and paternal anthropometrics with growth characteristics and the risk of overweight in pre-school children.
Population-based prospective cohort study from early foetal life onwards in the Netherlands.
Maternal pre-pregnancy anthropometrics and gestational weight gain, and paternal anthropometrics were related to foetal and post-natal growth measures and the risk of overweight until the age of 4 years. Analyses were based on 5674 mothers, fathers and their children.
Both pre-pregnancy maternal and paternal height, weight and body mass index were associated with corresponding foetal and post-natal anthropometric measures. Maternal body mass index had a significantly stronger effect on childhood body mass index than paternal body mass index. As compared to children from parents with normal body mass index, children from two obese parents had an increased risk of overweight at the age of 4 years (odds ratio 6.52 (95% confidence interval 3.44, 12.38). Maternal gestational weight gain was only among mothers with normal body mass index associated with body mass index and the risk of overweight in the children.
Maternal and paternal anthropometrics affect early growth in pre-school children differently. Gestational weight gain in mothers without overweight and obesity is related to the risk of overweight in early childhood.
关于母亲和父亲的人体测量学指标与纵向测量的幼儿期产后生长指标之间的关联，数据有限。
评估母亲和父亲的人体测量学指标与学龄前儿童生长特征及超重风险之间的关联。
荷兰一项从胎儿早期开始的基于人群的前瞻性队列研究。
将母亲孕前人体测量学指标、孕期体重增加情况以及父亲的人体测量学指标与胎儿期和产后生长指标以及4岁前超重风险相关联。分析基于5674名母亲、父亲及其子女的数据。
孕前母亲和父亲的身高、体重及体重指数均与相应的胎儿期和产后人体测量指标相关。母亲的体重指数对儿童期体重指数的影响显著强于父亲的体重指数。与父母体重指数正常的儿童相比，父母双方均肥胖的儿童在4岁时超重风险增加（比值比6.52（95%置信区间3.44，12.38））。仅在体重指数正常的母亲中，孕期体重增加与儿童的体重指数及超重风险相关。
母亲和父亲的人体测量学指标对学龄前儿童早期生长的影响不同。体重正常且无肥胖的母亲孕期体重增加与幼儿期超重风险相关。
