Jethava Ashif, Dasanu Constantin A
Department of Hospital Medicine, Saint Francis Hospital and Medical Center, Hartford CT, USA.
Conn Med. 2012 Nov-Dec;76(10):603-5.
Health-care professionals must be aware of the mandatory vitamin supplementation in patients status post bariatric surgery. A recent increase in the number of gastric bypass surgeries in US has been associated with a proportional increase in Wernicke encephalopathy reports. Subtle or atypical neurologic features are not uncommon. Our report is of a female patient with acute Wernicke encephalopathy accompanied by sensorineural hearing loss six weeks after bariatric surgery. The patient had only a partial recovery of her neurologic symptoms eightweeks after vigorous therapy for this condition. Symptomatic thiamine (vitamin B1) and vitamin B12 deficiencies are particularly concerning effects of bariatric procedures, as neurologic and cognitive deficits may be long lasting or even permanent despite aggressive replacement therapy.
医疗保健专业人员必须了解减肥手术后患者的强制性维生素补充情况。美国最近胃旁路手术数量的增加与韦尼克脑病报告数量的相应增加有关。轻微或非典型的神经学特征并不罕见。我们报告了一名女性患者,在减肥手术后六周出现急性韦尼克脑病并伴有感音神经性听力损失。在对该病症进行积极治疗八周后,患者的神经症状仅部分恢复。有症状的硫胺素(维生素B1)和维生素B12缺乏是减肥手术特别令人担忧的影响,因为尽管进行了积极的替代治疗,神经和认知缺陷可能会持续很长时间甚至是永久性的。