Dupré Marc Paul, Courtade-Saidi Monique
Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of Manitoba, Hôpital Général de Saint Boniface, 409, avenue Taché, Winnipeg, Manitoba, Canada R2H 2A6.
Ann Pathol. 2012 Dec;32(6):e47-51, 433-7. doi: 10.1016/j.annpat.2012.09.205. Epub 2012 Nov 20.
Immunocytochemistry as a routine ancillary test remains a distant reality for most diagnostic laboratories. Notable barriers to the mass deployment of ICC include: the large variety of specimen preparations, the small specimen size, lack of validation and lack of control specimens. As clinicians constantly strive to answer questions relating to diagnosis, therapy and prognosis with minimally invasive sampling techniques, the cytopathology community must endeavour to adopt ancillary specimen testing by ICC as a core element of diagnostic cytology.
免疫细胞化学作为一项常规辅助检测，对大多数诊断实验室来说仍是遥不可及的现实。免疫细胞化学大规模应用的显著障碍包括：样本制备种类繁多、样本量小、缺乏验证以及缺乏对照样本。由于临床医生不断努力通过微创采样技术回答与诊断、治疗和预后相关的问题，细胞病理学领域必须努力采用免疫细胞化学辅助样本检测作为诊断细胞学的核心要素。
