Budzyński Andrzej, Demczuk Sergiusz, Kumiega Beata, Migaczewski Marcin, Matłok Maciej, Zub-Pokrowiecka Anna
2 Department of General Surgery, Jagiellonian University Collegium Medicum, Cracow, Poland.
Wideochir Inne Tech Maloinwazyjne. 2011 Dec;6(4):249-55. doi: 10.5114/wiitm.2011.26261. Epub 2011 Dec 20.
The authors describe a case of sclerosing angiomatoid nodular transformation (SANT) of the spleen treated at the 2(nd) Department of Surgery, Jagiellonian University, Medical College. The patient was a 23-year-old woman. Clinically she presented with 2-year history of recurrent mild fever, diffuse joint pain, abdominal discomfort and iron deficiency anaemia of chronic disease. The laboratory tests revealed a non-characteristic chronic inflammatory response. A splenic solid lesion 9 cm in diameter was found on abdominal computed tomography. The patient underwent uneventful laparoscopic resection of the upper half of the splenic parenchyma. The resected tumour showed characteristic histological and immunophenotypical findings of SANT as previously described in the literature. In long-term follow-up, improvement of preoperative symptoms and abnormalities in the blood tests was documented.
作者描述了一例在雅盖隆大学医学院第二外科治疗的脾脏硬化性血管瘤样结节性转化(SANT)病例。患者为一名23岁女性。临床上,她有2年反复低热、弥漫性关节疼痛、腹部不适和慢性病性缺铁性贫血的病史。实验室检查显示为非特异性慢性炎症反应。腹部计算机断层扫描发现一个直径9厘米的脾脏实性病变。患者接受了脾脏实质上部的腹腔镜切除术,手术过程顺利。切除的肿瘤显示出如先前文献中所描述的SANT的特征性组织学和免疫表型表现。在长期随访中,术前症状和血液检查异常有所改善。