Department of Physiological Nursing, University of California, San Francisco, CA 94143, USA.
Arch Clin Neuropsychol. 2013 Mar;28(2):114-24. doi: 10.1093/arclin/acs101. Epub 2012 Dec 17.
Cognitive impairment is common among individuals with heart failure. The purpose of this study was to compare cognitive profiles of individuals with systolic and diastolic dysfunction. Eighty individuals with heart failure completed the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), Mini-Mental State Examination, Trail Making Test, and letter fluency. Approximately 25% of individuals with systolic dysfunction were impaired on the RBANS Total Scale score, compared with only 3% in the diastolic group. Additionally, individuals with systolic dysfunction scored lower than those with diastolic dysfunction on tests of immediate and delayed memory. The groups did not differ on tests of visuospatial skills, but there were mixed results on the RBANS Attention and Language subtests. Overall, the results of this study suggest that individuals with different types of cardiac dysfunction (systolic and diastolic dysfunction) demonstrate differential patterns of performance on neuropsychological tests. These findings have important clinical implications.
认知障碍在心力衰竭患者中很常见。本研究的目的是比较收缩功能障碍和舒张功能障碍患者的认知特征。80 名心力衰竭患者完成了重复性成套神经心理状态评估量表（RBANS）、简易精神状态检查、连线测试和字母流畅性测试。与舒张组的 3%相比，约 25%的收缩功能障碍患者在 RBANS 总评分上受损。此外，在即时记忆和延迟记忆测试中，收缩功能障碍患者的得分低于舒张功能障碍患者。两组在视空间技能测试上没有差异，但 RBANS 注意力和语言子测试的结果则混合不一。总的来说，这项研究的结果表明，不同类型的心脏功能障碍（收缩功能障碍和舒张功能障碍）患者在神经心理学测试中的表现模式存在差异。这些发现具有重要的临床意义。
