Arora Sandeep, Malik Ajay, Patil Chetan, Balki Anil
Department of Dermatology, Army College of Medical Sciences, Base Hospital, New Delhi, India.
Department of Pathology, Army College of Medical Sciences, Base Hospital, New Delhi, India.
Indian Dermatol Online J. 2015 Dec;6(Suppl 1):S17-20. doi: 10.4103/2229-5178.171055.
Annular elastolytic giant cell granuloma initially described by O'Brien in 1975 is a disorder of uncertain etiopathogenesis presenting with annular erythematous plaques predominantly on the sun-exposed areas. Hisptopathologically, it is characterized by elastin degenration, multinucleate giant cells, and elastophagocytosis. The authors came across 10 such cases, which were managed with hydroxychloroquine resulting in complete resolution in 4-6 months.
环状弹性组织溶解性巨细胞肉芽肿最初由奥布赖恩于1975年描述，是一种病因发病机制不明的疾病，主要表现为暴露于阳光下部位的环状红斑斑块。组织病理学上，其特征为弹性蛋白变性、多核巨细胞和弹性组织吞噬现象。作者遇到了10例此类病例，用羟氯喹治疗，4 - 6个月内完全消退。
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