Shariat Mansoureh, Pourpak Zahra, Khalesi Mojtaba, Kazemnejad Anoshirvan, Sharifi Laleh, Souzanchi Golnoosh, Movahedi Masoud, Gharagozlou Mohammad, Mahlooji Maryam, Moin Mostafa
Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Iran J Allergy Asthma Immunol. 2012 Dec;11(4):324-8.
Allergic rhinitis (AR) is a common global health problem with approximately one quarter of the world population affected. The quality of life (QOL) of sufferers with AR is significantly affected. The aim of this study was to evaluate the QOL of adults with AR. This study was designed for adults with AR above 18 years old. The study was conducted using a valid Rhinitis Quality of Life Questionnaires (RQLQ) which was completed for each patient during clinic visit and analyzed by applying statistical methods. One-hundred and ten AR patients participated in this study. Mean age of these patients was 32 years old and 62% were female. The correlation between severity of AR and QOL impairment was significant. Frequencies of mild persistent, moderate-severe persistent, mild intermittent and moderate-severe intermittent types of AR were 18%, 34.5%, 9% and 38%, respectively. Completed RQLQ indicated that about 55% of the cases were suffering from severe disturbances in their QOL. Furthermore, congestion (88%) was the most common symptom. The correlation between congestion and QOL reduction was significant. The correlation between congestion and sleep impairment was significant. AR was more common in young as well as female patients and their QOL was affected more than the others. The results showed a good relevancy between severity of symptoms and QOL scores. Consisting with ARIA classification, it was found that reduction in the quality of life is higher in patients with moderate-severe intermittent and persistent asthma. Nasal congestion was a bothersome and prevalent symptom in AR that was responsible for sleep problems. Therefore, nasal congestion was associated with sleep-disordered breathing, nocturnal sleep impairment, day time fatigue and somnolence which finally lead to QOL impairment.
变应性鼻炎（AR）是一个常见的全球性健康问题，全球约四分之一的人口受其影响。AR患者的生活质量（QOL）受到显著影响。本研究的目的是评估成年AR患者的生活质量。本研究针对18岁以上的成年AR患者设计。研究采用有效的鼻炎生活质量问卷（RQLQ），在门诊就诊时为每位患者填写，并应用统计方法进行分析。110名AR患者参与了本研究。这些患者的平均年龄为32岁，62%为女性。AR的严重程度与生活质量受损之间存在显著相关性。轻度持续性、中重度持续性、轻度间歇性和中重度间歇性AR类型的频率分别为18%、34.5%、9%和38%。完成的RQLQ表明，约55%的病例生活质量受到严重干扰。此外，鼻塞（88%）是最常见的症状。鼻塞与生活质量下降之间存在显著相关性。鼻塞与睡眠障碍之间存在显著相关性。AR在年轻患者和女性患者中更为常见，他们的生活质量受到的影响比其他人更大。结果显示症状严重程度与生活质量评分之间具有良好的相关性。与ARIA分类一致，发现中重度间歇性和持续性哮喘患者的生活质量下降更高。鼻塞是AR中一个令人烦恼且普遍存在的症状，它导致睡眠问题。因此，鼻塞与睡眠呼吸紊乱、夜间睡眠障碍、白天疲劳和嗜睡有关，最终导致生活质量受损。
