Early Childhood Interventions Program, Dept. of Psychology, Boston University, Boston, MA, USA.
J Am Acad Child Adolesc Psychiatry. 2013 Jan;52(1):26-36. doi: 10.1016/j.jaac.2012.10.001. Epub 2012 Dec 12.
Service use trends showing increased off-label prescribing in very young children and reduced psychotherapy use raise concerns about quality of care for early disruptive behavior problems. Meta-analysis can empirically clarify best practices and guide clinical decision making by providing a quantitative synthesis of a body of literature, identifying the magnitude of overall effects across studies, and determining systematic factors associated with effect variations.
We used random-effects meta-analytic procedures to empirically evaluate the overall effect of psychosocial treatments on early disruptive behavior problems, as well as potential moderators of treatment response. Thirty-six controlled trials, evaluating 3,042 children, met selection criteria (mean sample age, 4.7 years; 72.0% male; 33.1% minority youth).
Psychosocial treatments collectively demonstrated a large and sustained effect on early disruptive behavior problems (Hedges' g = 0.82), with the largest effects associated with behavioral treatments (Hedges' g = 0.88), samples with higher proportions of older and male youth, and comparisons against treatment as usual (Hedges' g = 1.17). Across trials, effects were largest for general externalizing problems (Hedges' g = 0.90) and problems of oppositionality and noncompliance (Hedges' g = 0.76), and were weakest, relatively speaking, for problems of impulsivity and hyperactivity (Hedges' g = 0.61).
In the absence of controlled trials evaluating psychotropic interventions, findings provide robust quantitative support that psychosocial treatments should constitute first-line treatment for early disruptive behavior problems. Against a backdrop of concerning trends in the availability and use of supported interventions, findings underscore the urgency of improving dissemination efforts for supported psychosocial treatment options, and removing systematic barriers to psychosocial care for affected youth.
服务使用趋势显示,非常年幼的儿童中超说明书用药的情况增加,心理治疗的使用减少,这引发了人们对早期破坏性行为问题的护理质量的担忧。元分析可以通过实证方法阐明最佳实践,并通过对文献进行定量综合,确定研究间总体效果的大小,以及确定与效果变化相关的系统因素,为临床决策提供指导。
我们使用随机效应元分析程序,实证评估心理社会治疗对早期破坏性行为问题的总体效果,以及治疗反应的潜在调节因素。符合选择标准的 36 项对照试验,共评估了 3042 名儿童(平均样本年龄 4.7 岁;72.0%为男性;33.1%为少数族裔青年)。
心理社会治疗对早期破坏性行为问题有显著且持续的效果(Hedges'g=0.82),其中行为治疗的效果最大(Hedges'g=0.88),样本中年龄较大和男性比例较高,以及与常规治疗相比(Hedges'g=1.17)。在各试验中,总体外部问题(Hedges'g=0.90)和对立与不服从问题(Hedges'g=0.76)的效果最大,相对而言,冲动和多动问题(Hedges'g=0.61)的效果最弱。
在缺乏评估精神药物干预的对照试验的情况下,这些发现提供了强有力的定量支持,即心理社会治疗应该成为早期破坏性行为问题的一线治疗方法。在支持性干预措施的可用性和使用情况令人担忧的背景下,这些发现强调了改善支持性心理社会治疗选择的传播工作,以及消除受影响青年接受心理社会护理的系统障碍的紧迫性。