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参考男性数据:化学元素的骨骼含量。

Data for the Reference Man: skeleton content of chemical elements.

作者信息

Zaichick Vladimir

机构信息

Department of Radionuclide Diagnostics, Medical Radiological Research Centre, Koroleva St.-4, Obninsk 249036, Kaluga Region, Russia.

出版信息

Radiat Environ Biophys. 2013 Mar;52(1):65-85. doi: 10.1007/s00411-012-0448-3. Epub 2012 Dec 25.

Abstract

This study was undertaken to provide reference values of chemical element mass fractions in intact bone of Reference (European Caucasian) Man/Woman. The rib bone samples investigated were obtained from autopsies of 84 apparently healthy 15-58-year-old citizens (38 females and 46 males) of a non-industrial region in the Central European part of Russia who had suffered sudden death. The mass fractions (mg/kg given on a wet mass basis) of 69 elements in these bone samples were measured by using neutron activation analysis with high-resolution spectrometry of short-lived and long-lived radionuclides, particle-induced gamma-ray emission, inductively coupled plasma atomic emission spectrometry, and inductively coupled plasma mass spectrometry including necessary quality control measures. Using published and measured data, mass fraction values of the 79 elements for the rib bone have been derived. Based on accepted rib to skeleton mass fractions and reference values of skeleton mass for Reference Man, the elemental burdens in the skeleton were estimated. These results may provide a representative bases for establishing related reference values for the Russian Reference Man/Woman and for revising and adding current reference values for the International Commission on Radiological Protection. The data presented will also be very valuable for many other applications in radiation protection, radiotherapy radiation dosimetry, and other scientific fields.

摘要

本研究旨在提供参考(欧洲高加索)男性/女性完整骨骼中化学元素质量分数的参考值。所研究的肋骨样本取自俄罗斯中欧部分一个非工业地区84名15 - 58岁明显健康的公民(38名女性和46名男性)的尸检,这些人死于猝死。通过使用具有短寿命和长寿命放射性核素高分辨率光谱的中子活化分析、粒子诱导γ射线发射、电感耦合等离子体原子发射光谱法以及电感耦合等离子体质谱法(包括必要的质量控制措施),测量了这些骨样本中69种元素的质量分数(以湿质量计,单位为mg/kg)。利用已发表的数据和测量数据,得出了肋骨中79种元素的质量分数值。根据公认的肋骨与骨骼质量分数以及参考男性骨骼质量的参考值,估算了骨骼中的元素负荷。这些结果可为建立俄罗斯参考男性/女性的相关参考值以及修订和补充国际放射防护委员会的现行参考值提供有代表性的依据。所呈现的数据对于辐射防护、放射治疗剂量测定以及其他科学领域的许多其他应用也将非常有价值。

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