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核分析及相关方法研究人体骨组织的化学元素。

Chemical elements of human bone tissue investigated by nuclear analytical and related methods.

机构信息

Department of Radionuclide Diagnostics, Medical Radiological Research Centre, Koroleva Str. 4, Obninsk 249036 Kaluga Region, Russia.

出版信息

Biol Trace Elem Res. 2013 Jun;153(1-3):84-99. doi: 10.1007/s12011-013-9661-4. Epub 2013 Apr 12.

DOI:10.1007/s12011-013-9661-4
PMID:23575902
Abstract

The mass fractions (in milligrams per kilogram given on a dry mass basis) of 69 chemical elements in the intact rib bone of 84 apparently healthy 15- to 58-year-old citizens (38 females and 46 males) of a nonindustrial region were investigated using five instrumental analytical methods: neutron activation analysis with high-resolution spectrometry of short- and of long-lived radionuclides, particle-induced gamma-ray emission spectrometry, inductively coupled plasma atomic emission, and mass spectrometry. The mass fractions of chemical elements were measured for rib bone of both males and females, taken separately and together. The present results indicate that rib bone can be used as exposure monitors in occupational medicine and environmental health studies to assess, or indicate, the body burden of Al, B, Ba, Be, Ca, Cr, F, Li, Mg, Na, Ni, P, Pb, rare-earth elements (REEs), Sr, and Zn. Our data show an exponential increase with the age of the content of REEs in the rib of people living in an ecologically safe region.

摘要

采用中子活化分析高分辨谱(短寿命和长寿命放射性核素)、粒子诱发γ射线发射光谱法、电感耦合等离子体原子发射光谱法和质谱法,研究了一个非工业地区 84 名 15 至 58 岁(38 名女性和 46 名男性)显然健康的公民完整肋骨中 69 种化学元素的质量分数(以干质量为基础,单位为毫克/千克)。分别和合并测量了男性和女性肋骨中化学元素的质量分数。目前的结果表明,肋骨可作为职业医学和环境卫生研究中的暴露监测器,用于评估或指示 Al、B、Ba、Be、Ca、Cr、F、Li、Mg、Na、Ni、P、Pb、稀土元素(REEs)、Sr 和 Zn 在体内的负荷。我们的数据显示,生活在生态安全地区的人的肋骨中 REEs 的含量随年龄呈指数增长。

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