Tiihonen J, Hari R, Kajola M, Nousiainen U, Vapalahti M
Low Temperature Laboratory, Helsinki University of Technology, Espoo, Finland.
Ann Neurol. 1990 Mar;27(3):283-90. doi: 10.1002/ana.410270310.
We used a large-area, 7-channel, first-order superconducting quantum interference device (SQUID) gradiometer to preoperatively determine the sites of epileptic foci in 2 patients with intractable temporal lobe seizures. The equivalent dipoles for the epileptic spikes were located with respect to external landmarks of the skull and in relation to the generation sites of magnetic auditory evoked responses. It was also possible, for the first time, to determine the location of the equivalent source using simultaneously measured data from seven locations only. The sites of the equivalent dipoles, in the right temporal lobe, agreed with the electrocorticographic and depth electrode recordings made during the operation.
我们使用了一种大面积、7通道、一阶超导量子干涉器件（SQUID）梯度仪，对2例难治性颞叶癫痫患者进行术前癫痫病灶定位。相对于颅骨的外部标志以及与磁听觉诱发反应的产生部位相关，确定癫痫棘波的等效偶极子位置。仅使用来自七个位置的同时测量数据首次确定等效源的位置也是可能的。等效偶极子在右侧颞叶的位置与手术期间进行的皮质脑电图和深部电极记录结果一致。
