Department of Healthcare Policy and Research, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA.
Gastrointest Endosc. 2013 Mar;77(3):436-46. doi: 10.1016/j.gie.2012.11.012. Epub 2013 Jan 4.
Serious GI adverse events in the outpatient setting were examined by polypectomy technique, endoscopist volume, and facility type (ambulatory surgery center and hospital outpatient department).
Retrospective follow-up study.
Ambulatory surgery and hospital discharge datasets from Florida (1997-2004) were used.
A total of 2,315,126 outpatient colonoscopies performed in patients of all ages and payers were examined.
Thirty-day hospitalizations because of colonic perforations and GI bleeding, measured as cumulative and specific outcomes, were investigated.
Compared with simple colonoscopy, the adjusted risks of cumulative adverse events were greater with the use of cold forceps (1.21 [95% CI, 1.01-1.44]), ablation (3.75 [95% CI, 2.97-4.72]), hot forceps (5.63 [95% CI, 4.97-6.39]), snares (7.75 [95% CI, 6.95-8.64]), or complex colonoscopy (8.83 [95% CI, 7.70-10.12]). Low-volume endoscopists had higher risks of adverse events (1.18 [95% CI, 1.07-1.30]). A higher risk of adverse events was associated with procedures performed in ambulatory surgery centers (1.27 [95% CI, 1.16-1.40]). Important findings were also reported for the analyses stratified by specific outcomes and procedures.
The study was constrained by limitations inherent in administrative data pertaining to a single state.
As the complexity of polypectomy increases, a higher risk of adverse events is reported. Using lower risk procedures when clinically appropriate or referring patients to high-volume endoscopists can reduce the rates of perforations and GI bleeding. Given the large number of colonoscopies performed in the United States, it is critical that the rates of adverse events be considered when choosing procedures.
本研究通过内镜检查技术、内镜医生工作量和医疗机构类型(门诊手术中心和医院门诊部门)来评估门诊环境下严重胃肠道不良事件的发生情况。
本研究为回顾性随访研究。
使用了来自佛罗里达州(1997-2004 年)的门诊手术和医院出院数据集。
共纳入了 2315126 例接受各种年龄段和支付方式患者的门诊结肠镜检查。
以 30 天住院率为指标,评估了因结肠穿孔和胃肠道出血导致的累积和特定不良事件。
与单纯结肠镜检查相比,冷活检钳(1.21 [95%可信区间,1.01-1.44])、消融术(3.75 [95%可信区间,2.97-4.72])、热活检钳(5.63 [95%可信区间,4.97-6.39])、圈套器(7.75 [95%可信区间,6.95-8.64])或复杂结肠镜检查(8.83 [95%可信区间,7.70-10.12])的累积不良事件风险更高。低工作量内镜医生的不良事件风险更高(1.18 [95%可信区间,1.07-1.30])。在门诊手术中心进行的操作与不良事件风险增加相关(1.27 [95%可信区间,1.16-1.40])。对特定结局和操作的分层分析也报告了重要发现。
本研究受到单一州行政数据固有局限性的限制。
随着息肉切除术的复杂性增加,不良事件的风险增加。在临床适当的情况下使用低风险的操作或将患者转介给高工作量的内镜医生,可降低穿孔和胃肠道出血的发生率。鉴于美国进行的结肠镜检查数量众多,在选择操作时必须考虑不良事件的发生率。