Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, (M3-B232), Seattle, WA 98109, USA.
J Community Health. 2013 Jun;38(3):546-53. doi: 10.1007/s10900-012-9649-6.
Cambodian Americans have high rates of chronic hepatitis B virus (HBV) infection. However, only about one-half of Cambodian Americans have been serologically tested for HBV. We conducted a randomized controlled trial to evaluate the impact of a lay health worker (LHW) intervention on HBV testing and knowledge levels among Cambodian Americans. The study group included 250 individuals who participated in a community based survey in metropolitan Seattle and had not been tested for HBV. Experimental group participants received a LHW intervention addressing HBV and control group participants received a LHW intervention addressing physical activity. Trial participants completed a follow-up survey 6 months after randomization. Over four-fifths (82 %) of randomized individuals participated in a LHW home visit and the follow-up survey response rate was 80 %. Among participants with follow-up data, 22 % of the experimental group and 3 % of the control group reported HBV testing (p < 0.001). The experimental and control group testing difference remained significant in an intent-to-treat analysis. The experimental group was significantly more likely than the control group to know that Cambodians have higher rates of HBV infection than whites, HBV cannot be spread by eating food prepared by an infected person, HBV cannot be spread by sharing chopsticks, and HBV cannot be spread by shaking hands. Our findings indicate LHW interventions are acceptable to Cambodian Americans and can positively impact both HBV testing and knowledge levels.
美国柬埔寨裔人群慢性乙型肝炎病毒 (HBV) 感染率较高。然而,只有大约一半的美国柬埔寨裔人群接受过 HBV 的血清学检测。我们开展了一项随机对照试验,以评估针对美国柬埔寨裔人群的社区卫生工作者 (LHW) 干预对 HBV 检测和知识水平的影响。研究组包括 250 名曾参与过西雅图大都市区社区调查且未接受过 HBV 检测的个体。实验组参与者接受了一项针对 HBV 的 LHW 干预,对照组参与者接受了一项针对身体活动的 LHW 干预。试验参与者在随机分组后 6 个月完成了随访调查。超过五分之四(82%)的随机个体接受了 LHW 的家访,随访调查的应答率为 80%。在有随访数据的参与者中,实验组的 22%和对照组的 3%报告接受了 HBV 检测(p<0.001)。意向性治疗分析显示,实验组和对照组的检测差异仍然显著。实验组比对照组更有可能知道柬埔寨裔人群的 HBV 感染率高于白种人、HBV 不能通过食用受感染者制备的食物传播、HBV 不能通过共用筷子传播以及 HBV 不能通过握手传播。我们的研究结果表明,LHW 干预措施可以被美国柬埔寨裔人群接受,并能积极影响 HBV 检测和知识水平。