State Key Laboratory of Chiroscience and Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
Org Lett. 2013 Jan 18;15(2):270-3. doi: 10.1021/ol303088z. Epub 2013 Jan 9.
A palladium-catalyzed C((sp2))-H bond oxygenation reaction is described. This protocol represents the first example of a C-H bond cleavage/C-O bond formation sequence, by employing a ketone moiety as the directing group. With this new catalytic method, a variety of ortho-acylphenols can be easily accessed from arylketones.
本文描述了钯催化的 C((sp2))-H 键氧化反应。该方案代表了首例利用酮作为导向基团的 C-H 键断裂/C-O 键形成序列。通过这种新的催化方法，可从芳基酮中轻松获得各种邻酰基苯酚。
