鸡血藤的化学成分。

Chemical constituents of Spatholobus suberectus.

机构信息

Changchun University of Chinese Medicine, Changchun 130117, China.

出版信息

Chin J Nat Med. 2012 Jan;10(1):32-5. doi: 10.1016/S1875-5364(12)60007-7.

DOI:10.1016/S1875-5364(12)60007-7

PMID:23302527

Abstract

AIM

To investigate chemical constituents of Spatholobus suberectus Dunn.

METHODS

Isolation and purification were carried out by column chromatographic methods. Compounds were characterized based on their physical characteristics and spectra data.

RESULTS

Seventeen compounds were isolated from ethanol extract of S. suberectus. The structures were elucidated as prestegane B (1), (2R, 3R)-buteaspermanol (2), (+)-medioresinol (3), (2R, 3R)-3,7-dihydroxyflavanone (4), benzeneethanol (5), 4, 7, 2'-trihydroxy-4'-methoxyisoflavanol (6), naringenin (7), blumenol A (8), protocatechuic acid ethyl ester (9), liquiritigenin (10), 7, 4'-dihydroxy-8-methoxy-isoflavone (11), 3, 5, 7, 3', 5'-pentahydroxyflavanone (12), protocatechuic acid (13), glycyroside (14), 8-methylretusin-7-O-β-D-glucopyranoside (15), 3, 3', 4', 5, 6, 7, 8-heptahydroxyflavan (16), and dulcisflavan (17).

CONCLUSION

All compounds are firstly isolated from the title plant and compounds 1, 3 were isolated from the Spatholobus genus for the first time.

摘要

目的

研究鸡血藤的化学成分。

方法

采用柱色谱方法进行分离和纯化。根据化合物的物理性质和光谱数据进行结构鉴定。

结果

从鸡血藤乙醇提取物中分离得到 17 个化合物。鉴定了它们的结构为：prestegane B（1）、（2R,3R）-buteaspermanol（2）、（+）-medioresinol（3）、（2R,3R）-3,7-二羟基黄烷酮（4）、苯乙醇（5）、4,7,2'-三羟基-4'-甲氧基异黄酮（6）、柚皮素（7）、blumenol A（8）、对羟基苯甲酸乙酯（9）、甘草素（10）、7,4'-二羟基-8-甲氧基异黄酮（11）、3,5,7,3',5'-五羟基黄烷酮（12）、原儿茶酸（13）、甘草苷（14）、8-甲基瑞特醇-7-O-β-D-吡喃葡萄糖苷（15）、3,3',4',5,6,7,8-七羟基黄烷（16）和dulcisflavan（17）。