来自显脉香茶菜的新对映-贝壳杉烷型和对映-柯烷型二萜类化合物。

New ent-abietane and ent-kaurane diterpenoids from Isodon rubescens.

作者信息

Liu Xu, Zhan Rui, Wang Wei-Guang, Du Xue, Li Xiao-Nian, Yang Jian-Hong, Zhang Peng, Li Yan, Pu Jian-Xin, Wu Ji-Zhou, Sun Han-Dong

机构信息

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, PR China.

出版信息

Chem Pharm Bull (Tokyo). 2013;61(1):90-5. doi: 10.1248/cpb.c12-00697.

DOI:10.1248/cpb.c12-00697

PMID:23302591

Abstract

Five new ent-abietane diterpenoids, ent-abierubesins A-E (1-5), and two new ent-kauranoids, hubeirubesins A and B (6, 7), together with three known diterpenoids (8-10), were isolated from the aerial parts of Isodon rubescens. Their structures were identified by means of extensive spectroscopic analysis, and the absolute stereochemistry of 1 was determined by single-crystal X-ray diffraction experiment.

摘要

从显脉香茶菜地上部分分离得到5个新的对映-贝壳杉烷二萜类化合物，对映-贝壳杉红素A-E（1-5），以及2个新的对映-贝壳杉烷型二萜类化合物，湖北红素A和B（6, 7），同时还得到3个已知的二萜类化合物（8-10）。通过广泛的光谱分析确定了它们的结构，并通过单晶X射线衍射实验确定了1的绝对立体化学结构。