Brayne C, Calloway P
Department of Community Medicine, Addenbrooke's Hospital, Cambridge, United Kingdom.
Acta Psychiatr Scand. 1990 Jan;81(1):6-8. doi: 10.1111/j.1600-0447.1990.tb06440.x.
It has been suggested that serum creatine kinase levels might be useful in the investigation of dementia. In this study serum creatine kinase BB (CKBB) isoenzyme levels were investigated in a community population of elderly women aged 70 to 80 years. Normative data for this group were compared with the findings in younger age groups. No relationship was found between levels of CKBB and level of dementia, or with the specific clinical diagnosis of senile dementia of the Alzheimer type, although a weakly positive relationship was found between CKBB and 3 cognitive scales.
有人提出，血清肌酸激酶水平可能有助于痴呆症的调查。在这项研究中，对70至80岁老年女性社区人群的血清肌酸激酶BB（CKBB）同工酶水平进行了调查。将该组的标准数据与年轻年龄组的结果进行了比较。虽然在CKBB与3种认知量表之间发现了微弱的正相关关系，但未发现CKBB水平与痴呆症水平之间或与阿尔茨海默型老年痴呆症的具体临床诊断之间存在关联。
