Zasler Nathan D, Martelli Michael F, Jacobs Harvey E
Concussion Care Center of Virginia, Richmond, VA, USA.
Handb Clin Neurol. 2013;110:377-88. doi: 10.1016/B978-0-444-52901-5.00032-0.
Neurobehavioral disorders are composed of a large group of behavioral impairments seen in association with brain disease (e.g., stroke, multiple sclerosis, dementia, and neuro-oncological conditions), transient as well as permanent brain impairments (e.g., metabolic and toxic encephalopathies), and/or injury (e.g., trauma, hypoxia, and/or ischemia). The neurorehabilitative assessment and management of such disorders is often poorly addressed in the context of overall neurological, psychiatric, and rehabilitative care. Too often, more basic, yet critical, aspects of behavioral assessment and treatment are not addressed or only superficially addressed by evaluating clinicians. Physicians often overly rely on pharmacological interventions as initial and/or sole treatment approaches rather than taking a pragmatic biopsychosocial approach that focuses on holistic disease state management. This chapter provides readers with an overview of the common behavioral impairments associated with brain dysfunction due to disease, injury, or toxicity. Details regarding the nature of impairments such as localization-related syndromes, affective disorders and personality disorders, among others are expounded. Principles of neurobehavioral assessment and treatment are examined including general guidelines for eliciting a history and physical, behavioral analysis, and functional behavioral assessment. General treatment caveats are provided including discussion of impairment and disability adaptation, and creation of positive behavioral supports. The topic of pharmacological management of neurobehavioral disorders is covered in numerous other references including Chapter 33 of this text.
神经行为障碍由一大类与脑部疾病(如中风、多发性硬化症、痴呆症和神经肿瘤疾病)、短暂性以及永久性脑损伤(如代谢性和中毒性脑病)和/或损伤(如创伤、缺氧和/或缺血)相关的行为损害组成。在整体神经科、精神科和康复护理的背景下,对此类障碍的神经康复评估和管理往往处理不当。通常,行为评估和治疗中更基本但至关重要的方面未得到解决,或者评估临床医生只是表面地处理这些方面。医生常常过度依赖药物干预作为初始和/或唯一的治疗方法,而不是采取注重整体疾病状态管理的务实生物心理社会方法。本章为读者概述了与因疾病、损伤或毒性导致的脑功能障碍相关的常见行为损害。阐述了诸如定位相关综合征、情感障碍和人格障碍等损害性质的详细信息。探讨了神经行为评估和治疗的原则,包括获取病史和体格检查、行为分析以及功能性行为评估的一般指南。提供了一般治疗注意事项,包括对损伤和残疾适应的讨论以及建立积极的行为支持。神经行为障碍的药物管理主题在许多其他参考文献中都有涉及,包括本文的第33章。