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本文引用的文献

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Fear of food as a treatment target: exposure and response prevention for anorexia nervosa in an open series.将食物视为治疗目标的恐惧:开放性系列中对神经性厌食症的暴露和反应预防。
Int J Eat Disord. 2012 May;45(4):615-21. doi: 10.1002/eat.20936. Epub 2011 May 3.
2
Eating disorder examination questionnaire and clinical impairment assessment questionnaire: general population and clinical norms for young adult women in Sweden.进食障碍检查问卷和临床损伤评估问卷:瑞典年轻成年女性的一般人群和临床常模。
Behav Res Ther. 2011 Feb;49(2):85-91. doi: 10.1016/j.brat.2010.10.010. Epub 2010 Nov 2.
3
Norms for the Eating Disorder Examination Questionnaire among female university students in Norway.挪威女大学生饮食失调检查问卷的规范
Nord J Psychiatry. 2010 Dec;64(6):428-32. doi: 10.3109/08039481003797235. Epub 2010 Apr 29.
4
Does cognitive-behavioral therapy response among adults with obsessive-compulsive disorder differ as a function of certain comorbidities?成人强迫症患者的认知行为疗法反应是否因某些共病而异?
J Anxiety Disord. 2010 Aug;24(6):547-52. doi: 10.1016/j.janxdis.2010.03.013. Epub 2010 Mar 31.
5
Mediation of symptom changes during inpatient treatment for eating disorders: the role of obsessive-compulsive features.住院治疗进食障碍期间症状变化的中介作用:强迫特质的作用。
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6
Rationale for the application of exposure and response prevention to the treatment of anorexia nervosa.应用暴露和反应预防治疗神经性厌食症的原理。
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What is the association between obsessive-compulsive disorder and eating disorders?强迫症与饮食失调之间有什么关联?
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Transdiagnostic cognitive-behavioral therapy for patients with eating disorders: a two-site trial with 60-week follow-up.针对饮食失调患者的跨诊断认知行为疗法:一项为期60周随访的双中心试验。
Am J Psychiatry. 2009 Mar;166(3):311-9. doi: 10.1176/appi.ajp.2008.08040608. Epub 2008 Dec 15.
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A randomized, controlled trial of cognitive-behavioral therapy for augmenting pharmacotherapy in obsessive-compulsive disorder.一项关于认知行为疗法辅助强迫症药物治疗的随机对照试验。
Am J Psychiatry. 2008 May;165(5):621-30. doi: 10.1176/appi.ajp.2007.07091440. Epub 2008 Mar 3.
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Practice guideline for the treatment of patients with obsessive-compulsive disorder.强迫症患者治疗实践指南。
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治疗伴有共病进食障碍的强迫症。

Treatment of obsessive-compulsive disorder complicated by comorbid eating disorders.

机构信息

Department of Psychiatry, Columbia University, New York, USA.

出版信息

Cogn Behav Ther. 2013;42(1):64-76. doi: 10.1080/16506073.2012.751124. Epub 2013 Jan 15.

DOI:10.1080/16506073.2012.751124
PMID:23316878
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3947513/
Abstract

PURPOSE

Eating disorders and obsessive-compulsive disorder (OCD) commonly co-occur, but there is little data for how to treat these complex cases. To address this gap, we examined the naturalistic outcome of 56 patients with both disorders, who received a multimodal treatment program designed to address both problems simultaneously.

METHODS

A residential treatment program developed a cognitive-behavioral approach for patients with both OCD and an eating disorder by integrating exposure and response prevention (ERP) treatment for OCD with ERP strategies targeting eating pathology. Patients also received a supervised eating plan, medication management, and social support. At admission and discharge, patients completed validated measures of OCD severity (the Yale-Brown Obsessive-Compulsive Scale--Self Report [Y-BOCS-SR]), eating disorder severity (the Eating Disorders Examination-Questionnaire), and depressive severity (the Beck Depression Inventory II [BDI-II]). Body mass index (BMI) was also measured. Paired-sample t-tests examined change on these measures.

MAIN RESULTS

Between 2006 and 2011, 56 individuals completed all study measures at admission and discharge. Mean length of stay was 57 days (SD = 27). Most (89%) were on psychiatric medications. Significant decreases were observed in OCD severity, eating disorder severity, and depression. Those with bulimia nervosa showed more improvement than those with anorexia nervosa. BMI significantly increased, primarily among those underweight at admission.

CONCLUSION

Simultaneous treatment of OCD and eating disorders using a multimodal approach that emphasizes ERP techniques for both OCD and eating disorders can be an effective treatment strategy for these complex cases.

摘要

目的

饮食障碍和强迫症(OCD)常同时发生,但针对这些复杂病例的治疗数据却很少。为了填补这一空白,我们考察了 56 例同时患有这两种疾病的患者的自然治疗结果,他们接受了一种多模式治疗方案,旨在同时解决这两个问题。

方法

一个住院治疗项目为同时患有 OCD 和饮食障碍的患者开发了一种认知行为方法,将针对 OCD 的暴露和反应预防(ERP)治疗与针对饮食失调的 ERP 策略相结合。患者还接受了监督饮食计划、药物管理和社会支持。在入院和出院时,患者完成了 OCD 严重程度的验证性测量(耶鲁-布朗强迫症量表自我报告 [Y-BOCS-SR])、饮食障碍严重程度(饮食障碍检查问卷)和抑郁严重程度(贝克抑郁量表第二版 [BDI-II])。还测量了体重指数(BMI)。配对样本 t 检验检验了这些测量值的变化。

主要结果

在 2006 年至 2011 年间,56 名个体完成了入院和出院时的所有研究测量。平均住院时间为 57 天(SD = 27)。大多数(89%)患者服用精神科药物。OCD 严重程度、饮食障碍严重程度和抑郁均显著下降。神经性贪食症患者比神经性厌食症患者改善更多。BMI 显著增加,主要发生在入院时体重不足的患者中。

结论

使用强调针对 OCD 和饮食障碍的 ERP 技术的多模式方法同时治疗 OCD 和饮食障碍,对于这些复杂病例可能是一种有效的治疗策略。